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TranscriptomicsGene expression profiling of mouse splenic Dendritic cells subsets
We describe a novel subset of CD8+ DCs in lymphoid organs of naïve mice characterized by expression of the CX3CR1 chemokine receptor. CX3CR1+CD8+ DCs lack hallmarks of classical CD8+ DCs, including IL12 secretion, the capacity to cross-present antigen and their developmental independence of the tran...
ORGANISM(S): Mus musculus 
2010-07-28 | E-GEOD-23212 | biostudies-arrayexpress
TranscriptomicsTranscriptome dynamics of developing photoreceptors in 3-D retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks
To define molecular mechanisms underlying rod and cone differentiation, we generated H9 human embryonic stem cell line carrying a GFP reporter that is controlled by the promoter of cone-rod homeobox (CRX) gene, the first known marker of post-mitotic photoreceptor precursors. CRXp-GFP reporter in H9 ...
ORGANISM(S): Homo sapiens 
2015-08-03 | E-GEOD-67645 | biostudies-arrayexpress
GenomicsThe In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J gene segments, has not previously been characterized in vivo. Here we demonstrate that RAG protein binding occurs in a highly focal manner to a small reg...
ORGANISM(S): Mus musculus 
2010-04-19 | E-GEOD-21207 | biostudies-arrayexpress
UnknownSurfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha.
Not available
S-EPMC2453510 | biostudies-literature
TranscriptomicsSIRT1 negatively regulates the differentiation of IL-9-producing CD4+T cells
Distinct metabolic programs support the differentiation of CD4+T cells into their separate lineages. In this study, we investigated metabolic mechanisms underlying the differentiation of IL-9 producing-CD4+T cells (TH9) in allergic airway inflammation and cancerous tumors. We found here that SIRT1 n...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-79607 | biostudies-arrayexpress
UnknownA transitional species of Daspletosaurus Russell, 1970 from the Judith River Formation of eastern Montana.
Not available
S-EPMC9703990 | biostudies-literature
UnknownMulticenter Evaluation of the BD Phoenix CPO Detect Test for Detection and Classification of Carbapenemase-Producing Organisms in Clinical Isolates.
Not available
S-EPMC7180248 | biostudies-literature
TranscriptomicsTranscriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterranea
The transcriptome of the planarian Schmidtea mediterranea is not well characterized. We have used RNA-Seq to characterize the transcriptome in both sexual and asexual strains of S. mediterranea from both untreated and irradiated animals. Moreover, we have performed RNA-Seq on RNA purified from FAC...
ORGANISM(S): Schmidtea mediterranea 
2012-04-24 | E-GEOD-34326 | biostudies-arrayexpress
TranscriptomicsCharacterization of the small RNA populations of developing Arabidopsis thaliana pollen.
Small RNA diversity and function has been widely characterized in various tissues of the sporophytic generation of the angiosperm model Arabidopsis thaliana. In contrast, there is limited knowledge about small RNA diversity and their roles in developing male gametophytes. We thus carried out small R...
ORGANISM(S): Arabidopsis thaliana 
2014-07-01 | E-GEOD-34190 | biostudies-arrayexpress
UnknownGrowth inhibition and apoptosis in colorectal cancer cells induced by Vitamin D-Nanoemulsion (NVD): involvement of Wnt/β-catenin and other signal transduction pathways.
Not available
S-EPMC6359839 | biostudies-literature
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