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TranscriptomicsCHD chromatin remodelers regulate separate gene sets and distinct stages of Dictyostelium development
We utilized RNA-seq to profile expression levels in wild type AX2 cells and three mutants for the CHD family of ATP-dependent chromatin remodellers in Dictyostelium discoideum. Total RNA was polyA enriched and sequenced at two stages of development: in the growth stage (0H) and in 5H cAMP pulsed cel...
ORGANISM(S): Dictyostelium discoideum 
2014-01-03 | E-GEOD-47222 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Dictyostelium discoides mutant cell type aspidocyte induced by heavy meatals and antibiotics
We describe the serendipitous discovery and first characterization of a new resistant cell type from Dictyostelium, which we propose to call the aspidocyte (aspida: Greek for shield). These cells are induced from amoebae by a range of toxins including heavy metals and antibiotics, and were first det...
ORGANISM(S): Dictyostelium discoideum 
2007-02-06 | E-SGRP-5 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Dictyostelium discoideum wild type and dupA null after infection with Legionella pneumophila
The social amoeba Dictyostelium discoideum is vulnerable to infection by the pathogen that causes Legionnaire's Disease, Legionella pneumophila. Dictystelium cells lacking the dual-specificity phospahatase DupA are at least partially resistant to infection, and strikingly the expression profile of u...
ORGANISM(S): Dictyostelium discoideum 
2009-09-24 | E-TABM-509 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Dictyostelium discoideum in response to infection with Pseudomonas aeruginosa PA01 and PA14 strains which differ in virulence
Pseudomonas aeruginosa is an opportunistic human pathogen, infecting immuno-compromised patients and causing persistent respiratory infections in people affected from cystic fibrosis. Pseudomonas strain Pseudomonas aeruginosa PA14 shows higher virulence than Pseudomonas aeruginosa PAO1 in a wide ran...
ORGANISM(S): Dictyostelium discoideum 
2008-07-09 | E-TABM-464 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 1h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50963 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 24h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50964 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. uninfected 48h p.i. (timecourse experiment)
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila in comparison to uninfected cells was investigated using DNA microarrays. Investigation of a 48 h time course of infection revealed several clusters of co-regulated genes, an enrichment of preferenti...
ORGANISM(S): Dictyostelium discoideum 
2013-09-25 | E-GEOD-50965 | biostudies-arrayexpress
TranscriptomicsDifferential expression of Dictyostelium discoideum AX2 upon infection with wt L. pneumophila JR32 vs. the L. pneumophila delta DotA mutant 24h p.i.
Differential gene expression of Dictyostelium discoideum after infection with Legionella pneumophila was investigated using DNA microarrays. A detailed analysis of the 24 h time point post infection was performed in comparison to three controls, uninfected cells and co-incubation with Legionella hac...
ORGANISM(S): Dictyostelium discoideum 
2013-09-07 | E-GEOD-50536 | biostudies-arrayexpress
GenomicsThe GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium
In many developmental systems, morphogenesis is coupled with dramatic changes in spatiotemporal gene expression, often orchestrated by the coordinated action of transcription factors. Development of the social soil amoebae Dictyostelium discoideum proceeds through a sequence of morphological and tra...
ORGANISM(S): Dictyostelium discoideum 
2015-07-02 | E-GEOD-63151 | biostudies-arrayexpress
TranscriptomicsStudy of circular RNA in Dictyostelium discoideum
RNA-Seq to discover circular RNA expression in Dictyostelium discoidieum with a shallow RNaseR treated RNA-Seq library; our goal was simply to prove existence of these molecules and hence samples were multiplexed with Neurospora Crassa using the same barcode. RNA-Seq on Rnase R treated RNA
ORGANISM(S): Dictyostelium discoideum 
2014-04-01 | E-GEOD-55429 | biostudies-arrayexpress
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