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UnknownNUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals.
Not available
S-EPMC2875033 | biostudies-literature
UnknownUpdate of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials.
Not available
S-EPMC7008866 | biostudies-literature
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - phosphoproteome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, the phosphoproteome was evaluated.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD042912 | Pride
Thp-1 Mcinp Didp Phosphoproteome Dinp Ohmphp Dphp Mhinp 
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - proteome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, untargeted proteomics was applied.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD043025 | Pride
Thp-1 Mcinp Didp Dinp Ohmphp Dphp Mhinp Proteome 
ProteomicsEffects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - redoxome
In this study, the effects of three high molecular weight phthalates (DINP, DIDP, DPHP) and their metabolites (MHINP, MCINP, OHMPHP) were investigated in THP-1 macrophages. For this purpose, the redoxome, including overall as well as reversible cysteine oxidation, was evaluated.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD043139 | Pride
Thp-1 Mcinp Didp Dinp Ohmphp Dphp Mhinp Redoxome 
TranscriptomicsRNA-Seq of in vitro thyroid mouse organoids exposed to a dose range of phthalates for 24 hours. ATAC-Seq of human epithelial thryoid cell line Nthy-ori 3-1 exposed to DEHP or DINP (1 uM) for 5 days
Mouse RNA-Seq: cells derived from recombinant embryonic stem cell line (A2LoxNkx2-1-Pax8) were used. Mouse embryonic stem cell-derived thyroid follicles were exposed to a dose range of phthalates (DEHP, DIDP, DINP at 1-10-100 nM-1-10 uM; DnOP at 2-20-200 nM-2-20 uM) for 24 hours. Every condition was...
ORGANISM(S): Mus musculus 
2023-09-03 | E-MTAB-12830 | biostudies-arrayexpress
UnknownEvaluation of the endocrine disrupting potential of Di-isodecyl phthalate.
Not available
S-EPMC11879679 | biostudies-literature
UnknownPlasticizers used in food-contact materials affect adipogenesis in 3T3-L1 cells.
Not available
S-EPMC5993210 | biostudies-literature
UnknownPrenatal phthalate exposure and adverse birth outcomes in the USA: a prospective analysis of births and estimates of attributable burden and costs.
Not available
S-EPMC11444077 | biostudies-literature
UnknownAmyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.
Not available
S-EPMC3314703 | biostudies-literature
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