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ProteomicsDYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant immunosuppressive and fibrotic tumor microenvironment (TME). Future therapeutic attempts therefore demand targeting of both compartments in order to be effective. We show here that Dual Specificity and Tyrosine...
ORGANISM(S): Mus Musculus 
2024-01-02 | MSV000093747 | MassIVE
GenomicsDeregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment - ChIPseq
PPARD and RXR genome wide binding in tumor associated macrophages from serous ovarian carcinoma was characterized.
ORGANISM(S): Homo sapiens 
2015-06-01 | E-MTAB-3166 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in MCF7 cells upon ISX treatment
MCF7 cells were treated with ISX, a novel GLI1 inducing HDAC-inhibitor
ORGANISM(S): Homo sapiens 
2021-04-28 | E-MTAB-10248 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in IMR32 cells upon ISX treatment
IMR32 neuroblastoma cells were treated with ISX, a novel GLI1 inducing HDAC-inhibitor
ORGANISM(S): Homo sapiens 
2021-04-28 | E-MTAB-10249 | biostudies-arrayexpress
TranscriptomicsDeregulation of PPAR-beta/delta target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment - RNAseq
The transcriptome of serous ovarian cancer tumor associated macrophages was characterized. Additionally, their transcription response to PPARD agonists and inverse agonists in cell culture was analyzed.
ORGANISM(S): Homo sapiens 
2015-05-31 | E-MTAB-3167 | biostudies-arrayexpress
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