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ProteomicsFiber-associated microbiota protects against diet-induced amelioration of the colonic mucus barrier
Here we have shown that diet-mediated alterations of the gut microbiota composition cause an erosion of the colonic mucus barrier. A compensatory increase in cellular mucus production by the host is not sufficient to re-establish the barrier, possibly due to a lacking increase in mucus secretion. Wh...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-22 | PXD006129 | Pride
Gut microbiota Obesity Fiber Mucus layer Metabolic disease Barrier function Western diet Diet-microbe-host interaction 
TranscriptomicsThe mechanism of promoting proliferation of rumen epithelial cells in Tan sheep by adding succinate to the diet based on the interaction between rumen microbiota and host.
A healthy rumen is crucial for normal growth and improved production performance of ruminant animals. Rumen microbes participate in and regulate rumen epithelial function, and the diverse metabolites produced by rumen microbes are important participants in rumen microbe-host interactions. SCFAs, as ...
ORGANISM(S): Ovis aries 
2023-06-12 | GSE233696 | GEO
UnknownDevelopmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe defects in weanling offspring mice.
Not available
S-EPMC6719698 | biostudies-literature
UnknownDietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion.
Not available
S-EPMC7244588 | biostudies-literature
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences
This SuperSeries is composed of the SubSeries listed below. Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolis...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-58087 | biostudies-arrayexpress
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences [30_week_Liver]
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), ...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-58086 | biostudies-arrayexpress
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences [8_week_ileal]
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), ...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-58085 | biostudies-arrayexpress
TranscriptomicsDextran sulfate sodium (DSS)-induced colitis in WT and NAPRT KO mice [scWT2]
NAPRT-mediated deamidated biosynthesis of nicotinamide adenine dinucleotide (NAD), an essential electron carrier for hundreds of biochemical reactions in all living cells, mediates the diet-microbe-host NAD metabolic interaction in mice. To study the function of this metabolic pathway in vivo, we re...
ORGANISM(S): Mus musculus 
2025-12-06 | GSE271836 | GEO
TranscriptomicsDextran sulfate sodium (DSS)-induced colitis in WT and NAPRT KO mice [NAPRTKODSS]
NAPRT-mediated deamidated biosynthesis of nicotinamide adenine dinucleotide (NAD), an essential electron carrier for hundreds of biochemical reactions in all living cells, mediates the diet-microbe-host NAD metabolic interaction in mice. To study the function of this metabolic pathway in vivo, we re...
ORGANISM(S): Mus musculus 
2025-12-06 | GSE271250 | GEO
TranscriptomicsAltering the intestinal microbiota during a critical developmental window has lasting metabolic consequences [RNA-Seq]
Acquisition of the intestinal microbiota begins at birth, and a stable microbial community develops from a succession of key organisms. Disruption of the microbiota during maturation by low-dose antibiotic exposure can alter host metabolism and adiposity. We now show that low-dose penicillin (LDP), ...
ORGANISM(S): Mus musculus 
2014-09-01 | GSE58089 | GEO
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