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MetabolomicsResponse to dietary carbohydrates in European seabass (Dicentrarchus labrax) muscle tissue as revealed by NMR-based metabolomics

INTRODUCTION: Feed optimization is a key step to the environmental and economic sustainability of aquaculture, especially for carnivorous species. Plant-derived ingredients can contribute to reduce costs and nitrogenous effluents while sparing wild fish stocks. However, the metab...

2019-01-22 | MTBLS619 | MetaboLights
MetabolomicsHigher Dietary Carbohydrates Detrimentally Impact Obesity-Associated Breast Cancer Chemoresistance
Not available
ORGANISM(S): Mus musculus 
ST001635 | MetabolomicsWorkbench
MetabolomicsMetabolite and gene expression profiles suggest a putative mechanism through which high dietary carbohydrates reduce the content of hepatic betaine in Megalobrama amblycephala
Not available
ORGANISM(S): Megalobrama amblycephala 
ST000966 | MetabolomicsWorkbench
MetabolomicsDietary carbohydrate and protein levels affect the growth performance of juvenile peanut worm (Sipunculus nudus): an LC–MS-based metabolomics study
The peanut worm (Sipunculus nudus) is an economically important fishery resource in China. To determine how dietary carbohydrate and protein levels affects the growth performance of juvenile S. nudus and identify the mechanisms underlying observedpatterns, five isoenergetic and isolipidic diets with...
2021-07-16 | MTBLS2887 | MetaboLights
MetabolomicsMicrobiome Metabolism of Dietary Phytochemicals Controls the Anticancer Activity of PI3K Inhibitors
Phosphatidylinositol 3-kinase (PI3K) signaling is both the effector pathway of insulin and among the most frequently activated pathways in human cancer. In murine cancer models, the efficacy of PI3K inhibitors is dramatically enhanced by a ketogenic diet, with a proposed mechanism involving dietary ...
2025-03-26 | MTBLS10944 | MetaboLights
ProteomicsDietary carbohydrates alter immune-modulatory functionalities and DNA inversions in Bacteroides thetaiotaomicron
The environment of gut bacteria is extremely dynamic. Environmental conditions were shown to affect microbial composition, however, their effects on bacterial functionality (e.g., immune-modulation activity) are mostly overlooked. Distinct strains of the same species, and even the same bacterial st...
ORGANISM(S): Bacteroides thetaiotaomicron CAG:40 
2025-05-04 | PXD060215 | Pride
Immune-modulator Bacteroides Dietary carbohydrates 
TranscriptomicsConsequences of exchanging carbohydrates for proteins in the cholesterol metabolism of mice fed a high-fat diet
Dietary proteins have profound effects on lipid metabolism but the mechanism remains to be elucidated. In the present study, we examined the temporal impact of dietary proteins in isoenergetic high fat diets on lipid metabolism of C57BL/6J mice. Mice were first fed a low protein (P) to carbohydrate ...
ORGANISM(S): Mus musculus 
2012-12-19 | E-GEOD-20260 | biostudies-arrayexpress
TranscriptomicsHigh dietary protein decreases fat deposition induced by high-fat and high-sucrose diet in rats
High-protein diets are known to reduce adiposity in the context of high carbohydrate and Western diets. However, few studies have investigated the specific high-protein effect on lipogenesis induced by a high-sucrose (HS) diet or fat deposition induced by high-fat feeding. We aimed to determine the ...
ORGANISM(S): Rattus norvegicus 
2015-09-01 | E-GEOD-47570 | biostudies-arrayexpress
TranscriptomicsDietary carbohydrates in land-locked Atlantic salmon (Salmo salar L.): impact on hepatic metabolism
A common-garden experiment was carried out to compare two genetically distinct strains of Atlantic salmon (Salmo salar) fed diets formulated with either high (CHO) or low (NoCHO) carbohydrate (starch). Twenty salmon from either a commercial farmed strain or a land-locked population were placed in tw...
ORGANISM(S): Salmo salar 
2018-12-31 | E-MTAB-6188 | biostudies-arrayexpress
TranscriptomicsMuscle Involvement in Preservation of Metabolic Flexibility by a Combination Treatment using n-3 PUFA and Rosiglitazone in Dietary-Obese Mice
Impaired resistance to insulin, the key defect in type 2 diabetes (T2D), is associated with a low capacity to adapt fuel oxidation to fuel availability, i.e., metabolic inflexibility. The hampered metabolic adaptability triggers a further damage of insulin signaling. Since skeletal muscle is the mai...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-36717 | biostudies-arrayexpress
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