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GenomicWhole Exome Sequencing in Tourette Disorder in Simplex Trios-TIC Genetics

The Tourette International Collaborative Genetics (TIC Genetics) Study is an international collaboration of scientists and clinicians specialized in Tourette Disorder (TD) from more than 20 sites across the United States, Europe, and South Korea. The study was established to further our understan...

phs001423 | dbGaP
TranscriptomicsThe role of Gaq in MLL leukemogenesis
Beta-catenin has a central role for self-renewal of leukemic stem cells in Mixed Lineage Leukemia (MLL)-arranged acute myeloid leukemia (AML), however its upstream modulators that can enhance this pathway remain largely unexplored. Through genome-wide gene expression analysis, we identified a previo...
ORGANISM(S): Mus musculus 
2016-02-25 | E-MTAB-4078 | biostudies-arrayexpress
TranscriptomicsModulation of T cell responses by type I interferons
Type I interferons (IFNs) play a key role in linking the innate and adaptive immune responses. IFNs can have both positive and negative effects on the development of memory CD8+ T cells, but their contribution to the priming of naïve T cells is unclear. Using OT-I TCR transgenic T cells, we show st...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-41381 | biostudies-arrayexpress
UnknownProminent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes.
Not available
S-EPMC12795280 | biostudies-literature
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