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MetabolomicsSex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics

Sex is a fundamental biological variable important in biomedical research, drug development, clinical trials, and prevention approaches. Among many organs, kidneys are known to exhibit remarkable structural, histological, and pathological differences between sexes. However, whether and how kidney...

2026-03-04 | MTBLS13977 | MetaboLights
MetabolomicsBiotransformation causes the sex-specific regulation of polychlorinated biphenyls during metamorphosis of silkworm (Bombyx mori) and their effect on the silkworm development

The decline in insect populations is indisputable. Currently, the effects of persistent organic pollutants on insect populations have not been sufficiently investigated. Maternal transfer of pollutants is considered to be an inherently correct reason for sex differences in pollutant le...

2025-09-09 | MTBLS12906 | MetaboLights
TranscriptomicsSex of Blood
Blood samples were taken at 1:00 pm +/- 1 h (Potassium-EDTA-monovettes, Sarstedt, Numbrecht, Germany) to control for circadian influences on gene expression. Blood was taken from normal male controls, normal female controls as well as different patients with disorders of sex development leading to a...
ORGANISM(S): Homo sapiens 
2009-07-13 | E-GEOD-11235 | biostudies-arrayexpress
TranscriptomicsSex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress
Depression and anxiety disorders are more prevalent in females, but the majority of research in animal models, the first step in finding new treatments, has focused predominantly on males. Here we report that exposure to subchronic variable stress (SCVS) induces depression-associated behaviors in fe...
ORGANISM(S): Mus musculus 
2016-08-04 | E-GEOD-85136 | biostudies-arrayexpress
TranscriptomicsThe X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner
This SuperSeries is composed of the following subset Series: GSE39472: X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner [ChIP-Seq data] GSE39473: The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agil...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-39222 | biostudies-arrayexpress
GenomicUCLA/Gabriella Miller Kids First Disorders of Sex Development Study

The Gabriella Miller Kids First Pediatric Research Program (Kids First) is a trans-NIH effort initiated in response to the 2014 Gabriella Miller Kids First Research Act and supported by the NIH Common Fund. This program focuses on gene discovery in pediatric cancers and structural birth defects a...

phs001178 | dbGaP
TranscriptomicsMycobacterium smegmatis: CarD depletion (mgm1703) vs Control (mgm1701)
Transcriptional profiling of Mycobacterium smegmatis comparing the effects of wild type levels of CarD expression with CarD depletion. Transcriptional profile of the mgm1701 control strain was compared with that of mgm1703, a strain where CarD transcription is regulated by a Tet-On system. Both stra...
ORGANISM(S): Mycobacterium smegmatis 
2010-05-16 | E-GEOD-15437 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of developmental and sex-regulated gene expression profiles in C. elegans
We have constructed DNA microarrays containing 17,871 genes, representing about 94% of the 18,967 genes currently annotated in the Caenorhabditis elegans genome. These DNA microarrays can be used as a tool to define a nearly complete molecular profile of gene expression levels associated with differ...
ORGANISM(S): Caenorhabditis elegans 
2005-11-18 | E-GEOD-3633 | biostudies-arrayexpress
TranscriptomicsMolecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 2)
In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabe...
ORGANISM(S): Rattus norvegicus 
2011-08-09 | E-GEOD-23809 | biostudies-arrayexpress
TranscriptomicsMolecular studies on sex-different control of the hepatic metabolism in relations to insulin sensitivity (set 1)
In this study we have analyzed gene expression and metabolite levels in the livers of male and female Zucker diabetic fatty (ZDF) rats. We speculated that the sex different development of diabetes in the ZDF animals presents the opportunity to relate gender to diabetes (since only males become diabe...
ORGANISM(S): Rattus norvegicus 
2011-08-09 | E-GEOD-23808 | biostudies-arrayexpress
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