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UnknownDilp-2-mediated PI3-kinase activation coordinates reactivation of quiescent neuroblasts with growth of their glial stem cell niche.
Not available
S-EPMC7282672 | biostudies-literature
UnknownPatterns of nucleotide diversity at the regions encompassing the Drosophila insulin-like peptide (dilp) genes: demography vs. positive selection in Drosophila melanogaster.
Not available
S-EPMC3538593 | biostudies-literature
UnknownExpression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan.
Not available
S-EPMC2698063 | biostudies-literature
TranscriptomicsRole of intracellular calcium in Drosophila larval growth and viability
Intracellular Ca2+ release through the Inositol 1,4,5-Triphosphate Receptor (InsP3R) is a feature of all multicellular organisms in which it shapes the temporal and spatial aspects of calcium signaling in cells, affecting several developmental and physiological processes. Mutants in the InsP3R gene ...
ORGANISM(S): Drosophila melanogaster 
2012-06-01 | E-GEOD-29736 | biostudies-arrayexpress
GenomicsRetrotransposon-based profiling of mammalian epigenomes: DNA methylation of IAP LTRs in embryonic stem, somatic and cancer cells
In this study, we analyzed the DNA methylation levels of 4799 IAP LTRs in three murine cell types: AB2.2 ES cells, somatic cells and a neuroblastoma cell line Neuro2A. According to the results, half of the IAP LTR retrotransposons show constant methylation patterns between the three cell types where...
ORGANISM(S): Mus musculus 
2015-06-15 | E-GEOD-60007 | biostudies-arrayexpress
ProteomicsDrosophila insulin-like peptides DILP2 and DILP5 stimulation global phosphoproteome
Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including growth, development, metabolism, stress responses and aging. Drosophila melanogaster IIS is propagated by eight Drosophila insulin-like peptides (DILPs), homologues of both mammalian insulin and IGFs, with ...
ORGANISM(S): Drosophila melanogaster Drosophila melanogaster (Fruit fly) 
2018-10-19 | PXD009240 | Pride
Insulin-like peptide Insulin/igf signaling Dilp Drosophila 
TranscriptomicsAn insulin-sensitive circular RNA that regulates lifespan in Drosophila
CircRNAs are a novel, poorly characterized class of non-coding RNAs that accumulate with age in neuronal tissues of diverse species. To characterize the role of circRNAs during ageing, we used RNA sequencing to analyse circRNA expression in Drosophila tissues (brain, thorax, gut and fat body) at dif...
ORGANISM(S): Drosophila melanogaster 
2020-06-26 | GSE130158 | GEO
Unknownp53- and ERK7-dependent ribosome surveillance response regulates Drosophila insulin-like peptide secretion.
Not available
S-EPMC4230838 | biostudies-literature
TranscriptomicsRole of intracellular calcium in Drosophila larval growth and viability
Intracellular Ca2+ release through the Inositol 1,4,5-Triphosphate Receptor (InsP3R) is a feature of all multicellular organisms in which it shapes the temporal and spatial aspects of calcium signaling in cells, affecting several developmental and physiological processes. Mutants in the InsP3R gene ...
ORGANISM(S): Drosophila melanogaster 
2012-06-02 | GSE29736 | GEO
UnknownGenome-wide analysis identifies Homothorax and Extradenticle as regulators of insulin in Drosophila Insulin-Producing cells.
Not available
S-EPMC9499297 | biostudies-literature
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