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MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
GenomicsRING1B calibrated ChIP-seq (cChIPseq) datasets for control mESCs and an Scc1-AID auxin-inducible degron.
We examined 3D chromatin structure in the absence of cohesin (Scc1-AID auxin-inducible degron) and a control line (E14-Tir1) and found that PRC1 core promoter component RING1B was one of the most enriched proteins. Hence, we performed calibrated ChIP-seq experiments on the control (E14-Tir1) and the...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7817 | biostudies-arrayexpress
ProteomicsHEK293T cells were transfected with Flag-tagged NLRP3 treated with or without nigericin (10 μM, 1 h).
In order to identificate NLRP3 acetylation, we utilized an acetylproteomic approach to identify the acetylation sites within NLRP3. We first reconstituted the NLRP3 inflammasome in HEK293T cells by co-transfected with plasmids encoding NLRP3, ASC, Caspase-1 and Pro-IL-1β, then stimulated the genetic...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-25 | PXD041763 | Pride
Hek293tcells， nlrp3 
TranscriptomicsSix in situ Hi-C libraries of control and mESC auxin-inducible degrons for Scc1 and Ring1b.
In this experiment, we've examined chromatin conformation differences of E14 mESC against cohesin and Ring1b degrons. We performed a modified in situ Hi-C protocol from (Rao et al., 2014) that can be found in detail at (Díaz et al., 2018). Samples were digested with MboI restriction enzyme. The aim ...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7816 | biostudies-arrayexpress
TranscriptomicsCapture-C experiments on auxin treated control (E14-Tir) and Scc1-AID, Ring1b-AID, Ring1b-AID-Scc1-AID and CTCF-AID (with and without a 6-hour auxin treatment) cells
The aim of the experiment was to gain a higher resolution for specific regions of interest to complement the Hi-C results. Capture-C experiments were performed on four-inducible degrons for Scc1, Ringb, Ring1b-Scc1 and CTCF, and Tir1 control, always in triplicates (three biological replicates per co...
ORGANISM(S): Mus musculus 
2020-01-23 | E-MTAB-7840 | biostudies-arrayexpress
UnknownTrade-off between flux efficiency and metabolic control shapes enzyme allocation
Not available
S-SCDT-10_1038-S44320-026-00250-5 | biostudies-other
UnknownDesign, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents.
Not available
S-EPMC4499832 | biostudies-literature
ProteomicsProteogenomic Integration Reveals Therapeutic Targets in Breast Cancer Xenografts
Huang K, Li S, Mertins P, Cao S, Gunawardena HP, Ruggles KV, et al., (2017) Nature Communications | 8:14864 | DOI: 10.1038/ncomms14864 | http://www.nature.com/articles/ncomms14864

Recent advances in mass spectrometry (MS) hav...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084249 | MassIVE
UnknownActivation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP.
Not available
S-EPMC3871513 | biostudies-literature
Unknown4D printing through vat photopolymerization of two-stage UV-curable liquid crystal elastomers.
Not available
S-EPMC12910083 | biostudies-literature
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