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ProteomicsBi-directional cell-pericellular matrix interactions direct stem cell fate
Modifiable hydrogels have revealed tremendous insight into how physical characteristics of cells’ 3D environment drive stem cell lineage specification. However, in native tissues, cells do not passively receive signals from their niche. Instead they actively probe and modify their pericellular space...
ORGANISM(S): Homo sapiens (Human) 
2018-11-23 | PXD009500 | Pride
Stem cells Matrix proteins Silac Lumos Orbitrap Interactions Fate 
TranscriptomicsGenome-wide identification of PIF3-binding sites and direct-target genes of PIF3 transcriptional regulation in skotomorphogenesis [RNA-Seq]
Dark-grown seedlings exhibit skotomorphogenic development. Genetic and molecular evidence indicates that a quartet of Arabidopsis Phytochrome (phy)-Interacting bHLH Factors (PIF1, 3, 4 and 5) are critically necessary to maintaining this developmental state, and that light activation of phy induces a...
ORGANISM(S): Arabidopsis thaliana 
2013-02-01 | E-GEOD-39214 | biostudies-arrayexpress
UnknownAutophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation.
Not available
S-EPMC8386598 | biostudies-literature
TranscriptomicsDifferentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens.
The mature eye lens contains a surface layer of epithelial cells called the lens epithelium that require a functional mitochondrial population to maintain the homeostasis and transparency of the entire lens. The lens epithelium overlies a core of terminally differentiated fiber cells that must degr...
ORGANISM(S): Gallus gallus 
2014-07-02 | E-GEOD-53976 | biostudies-arrayexpress
ProteomicsModular DNA origami compartments for the engineering of a protein unfolding and degradation pathway
Within the cell, chemical reactions are often confined and organized through a modular architecture. In this project, a cell-free nanoscale model of the proteasome was analyzed that exploits this compartmentalization principle to perform regulated protein unfolding and degradation. To this end, the ...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD050816 | Pride
Directional degradation Dna origami compartments Nanofactories 
UnknownDirectional translocation resistance of Zika xrRNA.
Not available
S-EPMC7385498 | biostudies-literature
UnknownEffect of directional pulling on mechanical protein degradation by ATP-dependent proteolytic machines.
Not available
S-EPMC5547649 | biostudies-literature
TranscriptomicsTotal RNA-seq upon degradation of OGT by siRNA
Evaluation of change in gene expression upon degradation of OGT by siRNA
ORGANISM(S): Mus musculus 
2024-08-31 | E-MTAB-14313 | biostudies-arrayexpress
UnknownLC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes.
Not available
S-EPMC8439105 | biostudies-literature
UnknownDirectional Amplified Photoluminescence through Large-Area Perovskite-Based Metasurfaces.
Not available
S-EPMC9955732 | biostudies-literature
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