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TranscriptomicsAffymetrix 500K SNP array data for Primary Effusion Lymphoma samples
Affymetrix 500K array was used to determine gross genomic aberrations in a panel of Primary Effusion Lymphoma (PEL) cell lines, specifically focusing on chromosome 10, which includes the Phosphatase and Tensin Homolog (PTEN) locus. 10 PEL cell lines were hybridized to the Affymetrix 500K array where...
ORGANISM(S): Homo sapiens 
2011-06-23 | E-GEOD-28684 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for Primary Effusion Lymphoma samples
Primary Effusion Lymphoma (PEL) is a Diffuse-Large B-cell Lymphoma (DLBCL) with poor prognosis. 100% of PEL carry the genome of Kaposi's Sarcoma-associated herpesvirus (KSHV) and approximately half are co-infected with Epstein-Barr virus (EBV). We profiled genomic aberrations in PEL using the Affyme...
ORGANISM(S): Homo sapiens 
2011-06-23 | E-GEOD-25839 | biostudies-arrayexpress
GenomicsThe Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus
KaposiM-bM-^@M-^Ys sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus which establishes latent infection in endothelial and B cells, as well as in primary effusion lymphoma (PEL). During latency, the viral genome exists as a circular DNA minichromosome (episome) and is packaged i...
ORGANISM(S): Human herpesvirus 8 
2013-09-05 | E-GEOD-50581 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mECK36: a cell and animal model of virally induced Kaposis sarcoma
Transfection of a Kaposi's sarcoma (KS) herpesvirus (KSHV) Bacterial Artificial Chromosome (KSHVBac36) into mouse bone marrow endothelial lineage cells generated a cell (mECK36) that induced KS-like tumors in mice. mECK36 formed KSHV-harboring vascularized spindle-cell sarcomas that were LANA+ and d...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6482 | biostudies-arrayexpress
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