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TranscriptomicsAnalysis of mRNA expression differences in the skin of Casp-8F/–K5-Cre and Casp-8F/+K5-Cre mice
This SuperSeries is composed of the following subset Series: GSE17344: Analysis of spatial mRNA expression differences in the skin of Casp-8F/–K5-Cre or Casp-8F/+K5-Cre mice GSE17345: Analysis of temporal mRNA expression changes in cultured keratinocytes from Casp-8F/–K5-Cre and Casp-8F/+K5-Cre mice...
ORGANISM(S): Mus musculus 
2009-07-29 | E-GEOD-17365 | biostudies-arrayexpress
TranscriptomicsTranscription profile of B cells isolated from peripheral lymph nodes of wild-type vs CCR7-/- mice
We investigated the transcriptional profile of B cells isolated from peripheral lymph nodes of CCR7-/-C57BL/6 and C57BL/6 mice respectively. B cells were sorted as follows: CD19+, CD3-, CD11c-, CD11b-, NK1.1-, GR-1-. Very few genes were differentially regulated in CCR7-/- B cells, however the expres...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-27885 | biostudies-arrayexpress
TranscriptomicsAnalysis of temporal mRNA expression changes in cultured keratinocytes from Casp-8F/M-bM-^@M-^SK5-Cre and Casp-8F/+K5-Cre mice
Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic skin inflammation in mice. Unlike similar inflammation resulting from arrest of NF-kB activation in the epidermal cells, the effect induced by caspase-8 deficiency did not de...
ORGANISM(S): Mus musculus 
2009-07-29 | E-GEOD-17345 | biostudies-arrayexpress
TranscriptomicsAnalysis of spatial mRNA expression differences in the skin of Casp-8F/–K5-Cre or Casp-8F/+K5-Cre mice
Expression of enzymatically inactive caspase-8, or deletion of caspase-8 from basal epidermal keratinocytes, triggers chronic skin inflammation in mice. Unlike similar inflammation resulting from arrest of NF-kB activation in the epidermal cells, the effect induced by caspase-8 deficiency did not de...
ORGANISM(S): Mus musculus 
2009-07-29 | E-GEOD-17344 | biostudies-arrayexpress
TranscriptomicsTranscription profile of CD103- vs CD103+ dendritic cells derived from CX3CR1+c-kit+- bone marrow cells (M1993 M2067)
We hypothesize that under homeostatic as well as inflammatory conditions circulating monocytes and/or their bone marrow-derived progenitors might contribute to the replenishment of CD103+ and CD103- DC in lymphoid and non-lymphoid compartments. To that end, bone marrow cells from CX3CR1+/gfp C57BL/6...
ORGANISM(S): Mus musculus 
2008-12-17 | E-GEOD-10882 | biostudies-arrayexpress
TranscriptomicsTHOC5 controls 3M-BM-4end-processing of immediate early genes via interaction with CPSF100
Transcription of immediate early genes (IEGs) in response to extrinsic and intrinsic signals is tightly regulated at multiple stages. THOC5, a member of the TREX (transcription/export) complex plays a role in expression of only a subset of constitutively active genes. In this report, we show that TH...
ORGANISM(S): Mus musculus 
2014-11-03 | E-GEOD-59561 | biostudies-arrayexpress
UnknownTranscriptional profiling of intestinal CD4(+) T cells in the neonatal and adult mice.
Not available
S-EPMC4583700 | biostudies-literature
TranscriptomicsTHOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation
THOC5, a member of the mRNA export complex, is essential for hematopoiesis in vivo and is required for CSF-1 induced macrophage differentiation, thereby playing a key role in the mRNA export of immediate early genes induced by CSF-1 stimulation. Hematopoiesis, growth, differentiation, and commitment...
ORGANISM(S): Mus musculus 
2013-12-24 | E-GEOD-41170 | biostudies-arrayexpress
UnknownPhosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination.
Not available
S-EPMC2672889 | biostudies-literature
UnknownImpact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus.
Not available
S-EPMC7662090 | biostudies-literature
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