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GenomicsCRISPRi on DMPK promoter
Highly Specific DMPK-promoter targeted by CRISPRi reverses DM1-associated defects in patient muscle cells
PRJEB60168 | ENA
TranscriptomicsComparative analysis of Mbl attenuation and CUG non-coding repeats expression in Drosophila larval muscles
Myotonic dystrophy type 1 (DM1) is a neuro-muscular disorder caused by CTG triplet expansion in the 3-UTR of the DMPK gene. Mutated transcripts aggregate in muscle nuclei and sequester the MBNL1 splicing factor. To assess the involvement of Mbl sequestration on transcriptpion deregulation in DM1, we...
ORGANISM(S): Drosophila melanogaster 
2013-04-01 | E-MTAB-1469 | biostudies-arrayexpress
UnknownSodium Channel Inhibitors Reduce DMPK mRNA and Protein.
Not available
S-EPMC5351028 | biostudies-literature
GenomicsBisulfite-seq: Analysis of CpG methylation at two CTCF binding sites flanking the CTG repeats of DMPK.
Bisulfite-seq: Analysis of CpG methylation at two CTCF binding sites flanking the CTG repeats of DMPK.
PRJNA623381 | ENA
UnknownEpigenetics of the myotonic dystrophy-associated DMPK gene neighborhood.
Not available
S-EPMC4863877 | biostudies-literature
UnknownDMPK mRNA Expression in Human Brain Tissue Throughout the Lifespan.
Not available
S-EPMC7862092 | biostudies-literature
UnknownCooperation meets competition in microRNA-mediated DMPK transcript regulation.
Not available
S-EPMC4627076 | biostudies-literature
UnknownSense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.
Not available
S-EPMC4560382 | biostudies-literature
UnknownIdentification and characterization of 5' CCG interruptions in complex DMPK expanded alleles.
Not available
S-EPMC5255948 | biostudies-literature
Genomics4C-seq: Three-dimensional chromatin interactions of FMR1, HTT, DMPK, and GFP viewpoints.
4C-seq: Three-dimensional chromatin interactions of FMR1, HTT, DMPK, and GFP viewpoints.
PRJNA623382 | ENA
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