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Twenty 3-day-old piglets that tested negative for both PEDV and PRRS antigens/antibodies were randomly divided into four groups: mock, DMSO, LR, and HDCA groups. The treatment groups received oral administration for five consecutive days prior to PEDV challenge. Intestinal contents were collected...

2025-07-04 | MTBLS12640 | MetaboLights
Genome-wide transcriptional profiling of Bj110 cells treated with P6 (20 uM for 24 h). Three independent biological materials were prepared for cells treated with P6 or DMSO (vehicle control). A total 6 arrays which includes dye swap were analyzed.
ORGANISM(S): Bradyrhizobium japonicum USDA 110 
Transcriptional profiling of human SH-SY5Y neuroblastoma cells comparing DMSO-treated control cells with those treated with 50 microM clioquinol (CQ) for 24 h. Two-condition experiment, DMSO vs. CQ . Biological replicates: 1DMSO, 1 CQ. One replicate per array.
ORGANISM(S): Homo sapiens 
DMSO effect on HepaRG differentiation
Expression profiling of from DMSO and SP600125 treated glutamatergic neurons reveals JNK target genes that are transcriptionally regulated by JNK signaling. SP600125 is a known JNK signaling inhibitor and therefore, we used this to test whether the expression of JNK bound genes is affected upon inhi...
ORGANISM(S): Mus musculus 
Gene signature determination of the effect of a new bromodomain inhibitor among a representative set of leukemic cell lines OTX015 vs. DMSO and JQ1 vs. DMSO
ORGANISM(S): Homo sapiens 
Cortistatin A (CA) is a highly selective inhibitor of the Mediator kinases CDK8 and CDK19. Using CA, we report here the first large-scale identification of Mediator kinase substrates in human cells (HCT116). Among over 16,000 quantified phosphosites, we identified 78 high-confidence Mediator kinase...
ORGANISM(S): Homo sapiens 
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