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UnknownA facile approach for development of a vaccine made of bacterial double-layered membrane vesicles (DMVs).
Not available
S-EPMC6205512 | biostudies-literature
ProteomicsPhosphatidic acid features double membrane vesicle formation during Hepatitis C and SARS-CoV-2 infection
Double membrane vesicles (DMVs) are used as replication organelles by pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required...
ORGANISM(S): Homo sapiens (Human) 
2022-01-24 | PXD029692 | Pride
Dmvs Lipid phosphatidic acid Sars-cov-2 Hepatitis c 
GenomicsA role of Polycomb in the maintenance of hypomethylation for DNA methylation valley
DNA methylation valleys (DMVs) are large loci that are devoid of DNA methylation in the genome. We show that DMVs are hypomethylated at most stages in development and are highly conserved across vertebrates. Importantly, DMVs are hotspots of regulatory regions for key developmental regulator genes. ...
ORGANISM(S): Mus musculus 
2017-12-24 | GSE102753 | GEO
ProteomicsCoronaviruses hijack Golgi apparatus derived COPI vesicles as a membrane source for viral DMV biogenesis
Using APEX2-mediated proximity labeling of SARS-CoV-2 nsp3, we identified the GBF1 as a key interacting protein within DMVs. Functional disruption of GBF1 or COPI not only suppressed viral RNA synthesis but also significantly reduced the size and abundance of DMVs and inhibits Golgi-DMVs colocalizat...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD070415 | Pride
Coronavirus replication 
GenomicsMus musculus
A role of Polycomb in the maintenance of hypomethylation for DNA methylation valley
PRJNA398611 | ENA
UnknownBrain deep medullary veins on 3-T MRI in a population-based cohort.
Not available
S-EPMC7922755 | biostudies-literature
UnknownRGD-expressed bacterial membrane-derived nanovesicles enhance cancer therapy via multiple tumorous targeting.
Not available
S-EPMC7847689 | biostudies-literature
UnknownGenome-wide analyses reveal a role of Polycomb in promoting hypomethylation of DNA methylation valleys.
Not available
S-EPMC5806489 | biostudies-literature
UnknownEpigenetic regulation of seed-specific gene expression by DNA methylation valleys in castor bean.
Not available
S-EPMC8886767 | biostudies-literature
UnknownDeep medullar veins: predictors of clinical progression in Alzheimer's disease.
Not available
S-EPMC12780641 | biostudies-literature
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