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TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-07-07 | E-GEOD-17179 | biostudies-arrayexpress
GenomicsCLC/DNR
CLC/DNR
PRJEB63229 | ENA
GenomicsPicea mariana cultivar:DNR
Picea mariana DNR Transcriptome - PmariDNR
PRJNA455449 | ENA
TranscriptomicsGenes rapidly regulated by Ara-C and DNR treatment of HL-60 AML cells and role of NADPH-oxidase derived ROS in DNR-induced gene expression
Daunorubicin (DNR) and Cytarabin (Ara-C) are the main chemotherapeutic drugs used for Acute Myeloid Leukemias (AML) treatment. However, their mode of action is not well understood. To decipher if these drug would induce rapid transcriptional reprogramming, we treated HL-60 AML cell line with DNR or ...
ORGANISM(S): Homo sapiens 
2017-12-31 | E-MTAB-4895 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of murine WT and DNR Tregs
Donminant negative transform growth factor receptor II (DNR) mice were served as a murine primary biliary cirrhrosis model. CD4+Foxp3+ Regulatory T cells (Tregs) play a critical role in self-tolerance and in regulating PBC. In order to determine whether DNR mice derived Tregs processed defective fu...
ORGANISM(S): Mus musculus 
2014-11-05 | E-GEOD-62964 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of murine WT and DNR Tregs
Donminant negative transform growth factor receptor II (DNR) mice were served as a murine primary biliary cirrhrosis model. CD4+Foxp3+ Regulatory T cells (Tregs) play a critical role in self-tolerance and in regulating PBC. In order to determine whether DNR mice derived Tregs processed defective fun...
ORGANISM(S): Mus musculus 
2014-11-05 | GSE62964 | GEO
TranscriptomicsTranscriptome response to nitric oxide in Pseudomonas aeruginosa
DNA microarray analysis was employed to investigate the transcriptome response to nitric oxide in Pseudomonas aeruginosa. We focused on the role played by the nitric oxide-response regulators DNR and FhpR and an oxygen-response regulator ANR in the response. The transcriptome profiles of the P. aeru...
ORGANISM(S): Pseudomonas aeruginosa 
2014-12-08 | E-GEOD-58862 | biostudies-arrayexpress
TranscriptomicsDefinition of the Pseudomonas aeruginosa Anr and Dnr Regulons
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable D...
ORGANISM(S): Pseudomonas aeruginosa 
2010-06-22 | GSE17179 | GEO
TranscriptomicsGene expression signatures in ex vivo Cytarabine (Ara-C) and Daunorubicin (Dnr) sensitive AML samples
Wide inter-individual variation in terms of outcome and toxic side effects of treatment exist among patients with AML receiving chemotherapy with cytarabine (Ara-C) and daunorubicin (Dnr). Drug resistance and relapse are considered major causes of treatment failure. Gene expression profiling was und...
ORGANISM(S): Homo sapiens 
2016-01-02 | GSE52919 | GEO
ProteomicsSUMOylation controls the rapid transcriptional reprogramming induced by chemotherapies in Acute Myeloid Leukemias
Genotoxicants have been used for decades as front-line therapies against cancer on the basis of their DNA-damaging actions. However, some of their non-DNA-damaging effects are also instrumental for killing dividing cells. We report here that the anthracycline Daunorubicin (DNR), one of the main drug...
ORGANISM(S): Homo sapiens (Human) 
2023-06-23 | PXD032956 | Pride
Sumo Acute myeloid leukemias 
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