Definition of the Pseudomonas aeruginosa Anr and Dnr Regulons

ABSTRACT: The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and survival during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network. Both are proposed to bind to a non-distinguishable DNA sequence named Anr box. The aim of this study was the identification of genes induced under anaerobic conditions in the P. aeruginosa wild type and identification of genes under control of the Anr or Dnr regulators. We performed three comparisons to identify genes induced under anaerobic denitrifying conditions in the P. aeruginosa wild type strain and genes which are under control of the Anr or Dnr regulators under these anaerobic conditions. Since the anr and dnr mutant strains do not grow

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Martin Eschbach 

PROVIDER: E-GEOD-17179 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress