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TranscriptomicsTranscription profiling of rat chronic exposure to cigarette smoke
Chronic obstructive pulmonary disease is a smoking-related disease that lacks effective therapies due partly to the poor understanding of disease pathogenesis. The aim of this study was to identify molecular pathways which could be responsible for the damaging consequences of smoking. To do this, w...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7079 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
TranscriptomicsTranscription profiling of neonatal and adult mouse natural killer cells
Comparing global gene expression of neonatal and adult natural killer cells to determine if differences in gene expression suggest that different developmental pathways during hematopoiesis are followed in the fetal and adult mouse to produce mature natural killer cells.
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-354 | biostudies-arrayexpress
GenomicsPerturbation of mRNP biogenesis reveals a dynamic landscape of the Rrp6-dependent surveillance machinery trafficking along the yeast genome (ChIP-seq dataset)
In order to dissect the nuclear RNA quality control (QC) mechanisms, we used a powerful assay based on global perturbation of mRNP biogenesis in yeast Saccharomyces cerevisiae by the bacterial Rho helicase. We have monitored the global RNA levels upon Rho activation and compare it to basal RNA level...
ORGANISM(S): Saccharomyces cerevisiae 
2019-12-04 | E-MTAB-7539 | biostudies-arrayexpress
TranscriptomicsCohesin localisation along fission yeast chromosomes delineates conserved mechanisms of binding
Cohesin holds sister chromatids together to enable their accurate segregation in mitosis. How, and where, cohesin binds to chromosomes are still poorly understood, and recent genome-wide surveys have revealed an apparent disparity between its chromosomal association patterns in different organisms. ...
ORGANISM(S): Schizosaccharomyces pombe 
2010-05-14 | E-GEOD-13517 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae response to Octanoic and Decanoic acids
In this study, we present an investigation of the yeast response to the exposure to octanoic and decanoic acids, two major fermentation inhibitors. Aerobically grown cells of Saccharomyces cerevisiae U13 wine strain have been exposed to 0,05 mM of octanoic and decanoic acid. We have compared the va...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-15 | E-GEOD-18480 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of epidydimal fat pads in mice following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin resistance. Switched the...
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-12 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in liver following high fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin Resistance. ...
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-10 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of epidydimal fat pads in mice at different time points following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. The diet was switched when mice were 5 weeks old, then samples taken at 2 days, 8 days, 3 weeks and 15 weeks.
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-9 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of muscle cells in mice at different different time points following muscle and normal diets to study insulin resistance and obesty
Gene transcription profiling in muscle following muscle versus normal diet in C57/Bl6 mice. Switched the diet when mice were 5 weeks old, then sampled at 8 days, 3 weeks and 15 weeks.
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-11 | biostudies-arrayexpress
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