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Transcriptomicscomparison of the transcriptome of the conditional afpig-a mutant and the wild-type
In order to gain a better understanding of the mechanism of increased cell death triggered by deficient GPI anchoring, we constructed a whole genome microarray using the Agilent eArray 5.0 program.The chip specification is 8M-CM-^W15K. The genome sequences were downloaded from the following site:htt...
ORGANISM(S): Aspergillus fumigatus 
2013-07-22 | E-GEOD-42499 | biostudies-arrayexpress
GenomicsMutant p53 cooperates with ETS2 to promote etoposide resistance [ChIP-Seq]
Mutant p53 (mtp53) promotes chemotherapy resistance through multiple mechanisms including disabling pro-apoptotic proteins and by regulating gene expression. Analysis of promoter regions identified through CHIP-on-CHIP and CHIP-SEQ platforms reveal that the ETS motif (EBS) is prevalent within predic...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-36749 | biostudies-arrayexpress
TranscriptomicsMutant p53 cooperates with ETS2 to promote etoposide resistance [ChIP-chip]
Mutant p53 (mtp53) promotes chemotherapy resistance through multiple mechanisms including disabling pro-apoptotic proteins and by regulating gene expression. Analysis of promoter regions identified through CHIP-on-CHIP and CHIP-SEQ platforms reveal that the ETS motif (EBS) is prevalent within predic...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-36751 | biostudies-arrayexpress
UnknownSynergistic roles of aquaporin 5 and intra- and extracellular carbonic anhydrases in promoting CO<sub>2</sub> diffusion across the Xenopus oocyte plasma membrane.
Not available
S-EPMC12871926 | biostudies-literature
GenomicsA Novel HDAC Complex in the Control of Transcription and Genome Stability
The acetylation state of histones, controlled by histone acetyltransferases and deacetylases, profoundly affects DNA transcription and repair by modulating chromatin accessibility to the cellular machinery. The Schizosaccharomyces pombe HDAC Clr6 (human HDAC1) binds to different sets of proteins tha...
ORGANISM(S): Schizosaccharomyces pombe 
2014-07-10 | E-GEOD-57040 | biostudies-arrayexpress
TranscriptomicsGenome-wide control of RNA polymerase II activity by cohesin (tiling)
Cohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of cohesin are not well understood, but are vital: gene expression and development are altered by modest changes in cohesin function that do not disrupt ch...
ORGANISM(S): Drosophila melanogaster 
2013-04-24 | E-GEOD-42360 | biostudies-arrayexpress
MetabolomicsGeographic variation of mutagenic exposures in kidney cancer genomes

International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden1. This pertains to clear cell renal cell carcinoma (ccRCC), fo...

2024-03-26 | MTBLS9394 | MetaboLights
TranscriptomicsImprinted expression is different in visceral yolk sac and cystic embryoid body endoderm
Genomic imprinting is an epigenetic phenomenon resulting in parent-of-origin mono-allelic expression of a small subset of mammalian genes. Imprinted genes have been categorized into two groups: multi lineage (ML) imprinted genes that can show imprinted expression in both embryonic and extra-embryoni...
ORGANISM(S): Mus musculus 
2015-07-22 | E-GEOD-56276 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile and small RNA transcriptome in the Squalius alburnoides complex
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Squalius pyrenaicus 
2013-01-02 | E-GEOD-38799 | biostudies-arrayexpress
TranscriptomicsExpression data from C2C12 cells with or without Smad3 overexpression
The goal of this study was to identify genes in C2C12 myoblasts whose expression was altered by overexpression of Smad3. Four total samples were analyzed. Two biological replicates were prepared from C2C12 cells infected with retroviral vector encoding wildtype Smad3 and exposed for 24 hours to 100 ...
ORGANISM(S): Mus musculus 
2011-10-20 | E-GEOD-30459 | biostudies-arrayexpress
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