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TranscriptomicsExpression data from bone marrow derived- and tumor induced- CD11b+ MDSC
Tumor growth is associated with a profound alteration of myelopoiesis, leading to recruitment of immunosuppressive cells known as myeloid-derived suppressor cells (MDSCs). Analyzing the cytokines affecting myelo-monocytic differentiation produced by various experimental tumors, we found that GM-CSF...
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-21927 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse CD11b cells purified from mouse spleen from umor-free and tumor-bearing mice
Active suppression of tumor-specific T lymphocytes can limit the immune-surveillance and immunotherapy efficacy. While tumor-recruited CD11b+ myeloid cells are known mediators of tumor-associated immune dysfunction, the true nature of these suppressive cells and the fine biochemical pathways governi...
ORGANISM(S): Mus musculus 
2009-04-29 | E-GEOD-5455 | biostudies-arrayexpress
UnknownAn original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.
Not available
S-EPMC4478717 | biostudies-literature
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