Sort   by:  
 Page size 
TranscriptomicsCommonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin-remodeling and splicing
Acute myeloid leukemia (AML) is characterized by molecular heterogeneity. As commonly altered genomic regions point to candidate genes involved in leukemogenesis, we used microarray-based comparative genomic hybridization and single nucleotide polymorphism profiling data of 391 AML cases to further ...
ORGANISM(S): Homo sapiens 
2012-09-27 | E-GEOD-38987 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of alternative splicing points to novel leukemia-relevant genes in acute myeloid leukemia.
Alternative mRNA splicing represents an effective mechanism of regulating gene function and is a key element to increase the coding capacity of the human genome. Today, an increasing number of reports illustrates that aberrant splicing events are common and functionally important for cancer developm...
ORGANISM(S): Homo sapiens 
2014-12-15 | E-GEOD-21337 | biostudies-arrayexpress
Sort   by:  
 Page size