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ProteomicsReceptor kinase signalling of BRI1 and SIRK1 is tightly balanced by their interactomes as revealed from domain-swap chimaera in AE-MS approaches.
Plants response to different external and internal stimulation by activation of signal transduction pathways. Receptor kinases are localized at plasma membrane and were characterized to be involved in perception of signals at the cell surface. Here we use affinity enrichment mass spectrometry acquis...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-06 | PXD035647 | Pride
Cell expansion Lrr-receptor kinase Signaling cross-talk Signaling specificity Domain-swap chimera 
ProteomicsReceptor kinase signalling of BRI1 and SIRK1 is tightly balanced by their interactomes as revealed from domain-swap chimaera in AE-MS approaches.
Plants response to different external and internal stimulation by activation of signal transduction pathways. Receptor kinases are localized at plasma membrane and were characterized to be involved in perception of signals at the cell surface. Here we use affinity enrichment mass spectrometry acquis...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-06 | PXD044354 | Pride
Lrr-receptor kinase Supervised machine learning Signaling specificity Affinity enrichment mass-spectrometry (ae-ms) Domain-swap chimera 
UnknownReceptor Kinase Signaling of BRI1 and SIRK1 Is Tightly Balanced by Their Interactomes as Revealed From Domain-Swap Chimaera in AE-MS Approaches.
Not available
S-EPMC11585773 | biostudies-literature
UnknownA domain swap approach reveals a role of the plant wall-associated kinase 1 (WAK1) as a receptor of oligogalacturonides.
Not available
S-EPMC2889104 | biostudies-literature
UnknownDeterminants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.
Not available
S-EPMC2586577 | biostudies-literature
UnknownEmergence and subsequent functional specialization of kindlins during evolution of cell adhesiveness.
Not available
S-EPMC4325847 | biostudies-literature
TranscriptomicsAn ENU-induced point mutation in the mouse Btaf1 gene causes post-gastrulation embryonic lethality and protein instability
The mouse Btaf1 gene, an ortholog of yeast MOT1, encodes a highly conserved general transcription factor. The function of this SNF-2 like ATPase has been studied mainly in yeast and human cells, which has revealed that it binds directly to TBP, forming the B-TFIID complex. This complex binds to cor...
ORGANISM(S): Mus musculus 
2011-01-21 | E-GEOD-26743 | biostudies-arrayexpress
TranscriptomicsGrowth arrest of human thyroid cancer cells 8505C after inhibition of TTF-1 transcriptional activity
Background: thyroid transcription factor-1 (TTF-1) is known to play key roles in thyroid organogenesis, in thyroid cell proliferation and in the expression of genes involved in thyroid differentiated function. Objective: to understand why many human thyroid cancer cell lines keep producing TTF-1 d...
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-58587 | biostudies-arrayexpress
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