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Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
Using two different approaches to CK2alpha-silencing, we have used RNA-seq to identify variation in gene-expression of important cell cycle regulators with relevance to heart-associated defects.
ORGANISM(S): Rattus norvegicus 
Cells have the ability to respond and adapt to environmental changes through the activation of stress-activated protein kinases (SAPKs). Although it has been shown that p38 SAPK signalling participates in the regulation of gene transcription, there is not a comprehensive genome-wide transcription st...
ORGANISM(S): Mus musculus 
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