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ProteomicsMonitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts
Master transcription factor (mTF) has been recognized as topmost regulatory hierarchy in cell fate determination. However, the direct transcriptional targets of mTFs, and how the interplay between these transcriptional targets and their associated RNA-binding proteins (RBPs) orchestrate the realisat...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-28 | PXD043911 | Pride
Mouse Mesc 
ProteomicsFLAG-TCF21 interactome in HCT116 and TPCs by IP-MS
This project presents the proteomic profiling of protein complexes associated with the transcription factor TCF21, achieved through affinity purification coupled with mass spectrometry (AP-MS). The study aimed to comprehensively map the TCF21 interactome in two distinct cellular models: the human co...
ORGANISM(S): Homo Sapiens 
2025-12-12 | PXD071976 |
ProteomicsExploration of the antioxidant effect of spermidine on the ovary and screening and identification of differentially expressed proteins
Spermidine is a naturally occurring polyamine compound that has many biological functions, such as inducing autophagy and anti-inflammatory and anti-aging effects. In this study, ICR mice were fed exogenous spermidine drinking water for three months to explore the regulation of ovarian function by s...
ORGANISM(S): Mus Musculus 
2022-12-12 | PXD038755 |
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