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TranscriptomicsInvestigation of the mechansim underlying the inflammatory phenotype in Group A ependymoma
Inflammatory response has been identified as a molecular signature of high-risk Group A ependymoma (EPN). To better understand the biology of this phenotype and aid therapeutic development, transcriptomic data from Group A and B EPN patient tumor samples, and additional malignant and normal brain da...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-66354 | biostudies-arrayexpress
TranscriptomicsExpression data from human brain tumors and human normal brain
The characteristics of immune cells infiltrating pediatric brain tumors is largely unexplored. A better understanding of these characteristics will provide a foundation for development of immunotherapy for pediatric brain tumors. Gene expression profiles were used to identify immune marker gene that...
ORGANISM(S): Homo sapiens 
2013-08-25 | E-GEOD-50161 | biostudies-arrayexpress
UnknownInvestigation of the mechansim underlying the inflammatory phenotype in Group A ependymoma
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-66354 | biostudies-other
TranscriptomicsIdentification of targets for rational pharmacological therapy in childhood craniopharyngioma
Introduction: Pediatric adamantinomatous craniopharyngioma (ACP) is a histologically benign but clinically aggressive brain tumor that arises from the sellar/suprasellar region. Despite a high survival rate with current surgical and radiation therapy (75-95% at 10 years), ACP is associated with debi...
ORGANISM(S): Homo sapiens 
2015-04-18 | E-GEOD-68015 | biostudies-arrayexpress
TranscriptomicsExpression data from high grade astrocytoma surgical samples
Survival in the majority of high grade astrocytoma (HGA) patients is very poor, with only a rare population of long-term survivors. A better understanding of the biological factors associated with long-term survival in HGA would aid development of more effective therapy and prognostication. We used ...
ORGANISM(S): Homo sapiens 
2011-10-31 | E-GEOD-33331 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ependymoma tumors with known clinical outcomes
Ependymoma, the 3rd most common brain tumor in children, recurs in approximately 50% of patients. There is currently no robust marker that predicts for recurrence, which is a significant clinical problem; We used global gene expression profiling of 19 patient surgical samples obtained at initial dia...
ORGANISM(S): Homo sapiens 
2009-10-10 | E-GEOD-16155 | biostudies-arrayexpress
UnknownExpression data from high grade astrocytoma surgical samples
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-33331 | biostudies-other
TranscriptomicsPediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Rhabdoid tumors (RTs) are aggressive tumors of early childhood that occur most often in brain (AT/RTs) or kidney (KRTs). Regardless of location, they are characterized by loss of functional SMARCB1 protein, a component of the SWI/SNF chromatin remodeling complex. The aim of this study was to determi...
ORGANISM(S): Homo sapiens 
2013-01-21 | E-GEOD-35493 | biostudies-arrayexpress
UnknownTranscription profiling of human ependymoma tumors with known clinical outcomes
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-16155 | biostudies-other
UnknownDifferential phagocytosis induces diverse macrophage activation states in malignant gliomas.
Not available
S-EPMC12414246 | biostudies-literature
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