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GenomicsMulti-Dot/Icm effector deletion mutants reveal distinct host transcriptional responses in Legionella pneumophila infected macrophages
Multi-Dot/Icm effector deletion mutants reveal distinct host transcriptional responses in Legionella pneumophila infected macrophages
PRJEB108343 | ENA
TranscriptomicsMulti-Dot/Icm effector deletion mutants reveal distinct host transcriptional responses in Legionella pneumophila infected macrophages
Legionella pneumophila is an intracellular pathogen that uses a type IV secretion system called Dot/Icm to translocate over 330 effector proteins into the infected cells. To explore the collective impact of Dot/Icm effectors on host cell processes, we created a library of 14 L. pneumophila genomic m...
ORGANISM(S): Homo sapiens 
2026-02-28 | E-MTAB-16655 | biostudies-arrayexpress
UnknownMolecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS.
Not available
S-EPMC6588468 | biostudies-literature
UnknownStructure and Function of the Dot/Icm T4SS.
Not available
S-EPMC10055428 | biostudies-literature
UnknownMultiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer.
Not available
S-EPMC321768 | biostudies-literature
UnknownComprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila.
Not available
S-EPMC3052360 | biostudies-literature
UnknownDevelopmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System.
Not available
S-EPMC9584302 | biostudies-literature
UnknownDot/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages.
Not available
S-EPMC3163939 | biostudies-literature
UnknownRapid escape of the dot/icm mutants of Legionella pneumophila into the cytosol of mammalian and protozoan cells.
Not available
S-EPMC1932949 | biostudies-literature
UnknownIdentification of ElpA, a Coxiella burnetii pathotype-specific Dot/Icm type IV secretion system substrate.
Not available
S-EPMC4333474 | biostudies-literature
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