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Increasing evidences are revealing the important biological functions of apoptotic bodies (ABs). Here we identified the proteomic profiles of ABs from osteoclasts of distinct differentiation stages and investigated the potential functions. ABs were isolated from apoptotic bone marrow macrophages (BM...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD017245 | Pride
Total RNA were extracted from osteoclasts differentiated from RAW264.7 cells at different stages: Monocytes (0h), Pre-osteoclasts (24h), Mature osteoclasts (72h) and activated osteoclasts (96h). LncRNA and mRNA expression profiles were decided by microarray. RAW264.7 cells were cultured with RANKL (...
ORGANISM(S): Mus musculus 
miRNAs are regulators of gene expression in plants and animals. Their biogenesis is precisely controlled to secure normal development of organisms. Here we report that TOUGH (TGH) is a novel component of DCL1-HYL1-SE complex that processes of primary transcripts of miRNAs (pri-miRNAs) into miRNAs i...
ORGANISM(S): Arabidopsis thaliana 

To investigate the metabolites and pathways modulated by BCG in RANKL-differentiated macrophages, thereby elucidating the metabolic mechanisms underlying BCG-induced macrophage activation, BMMs were stimulated with 50 ng/mL RANKL for 5 days to generate osteoclast-like cells. Subsequently, one gro...

2026-03-31 | MTBLS12992 | MetaboLights
Nitrogen fixation is a highly energy-demanding process and highly regulated at multiple levels. The two major signals that regulate nitrogen fixation in most diazotrophs are oxygen and ammonia. In order to study the complex regulated mechanism and to highlight the complete nitrogen fixing system in ...
ORGANISM(S): Pseudomonas stutzeri A1501 
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