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TranscriptomicsComparison of polysomal profiles of murine adult normal, tumor, and recruited olig2 cells
Comparison of polysomal profiles of murine adult olig2 cortical progenitors, murine tumor olig2 cells derived from hPDGF-B-driven glioblastomas, and murine olig2 proliferative recruited glioma cells contributing to the tumor mass but not derived from the cell of origin An unbiased way to define a c...
ORGANISM(S): Mus musculus 
2011-06-17 | E-GEOD-30016 | biostudies-arrayexpress
Transcriptomicsc-MET inhibitor inducing KSHV+ primary effusion lymphoma apoptosis
KSHV is a principal causative agent of primary effusion lymphoma (PEL). Despite this knowledge about the close relationship between HGF/c-MET network and solid tumors development, the role of HGF/c-MET in KSHV-related malignancies remains mostly unclear. We report that HGF/c-MET pathway is highly ac...
ORGANISM(S): Homo sapiens 
2016-01-05 | E-GEOD-70594 | biostudies-arrayexpress
TranscriptomicsResponse of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer.
Objectives ELB-21 is a pyrrolo[2,1-c][1,4]benzodiazepine dimer with potent antistaphylococcal activity; it binds covalently to guanine residues on opposing strands of duplex DNA, interfering with regulatory proteins and transcription elongation in a sequence-selective manner. Transcriptional and pro...
ORGANISM(S): Staphylococcus aureus 
2009-09-18 | E-BUGS-79 | biostudies-arrayexpress
UnknownMolecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.
Not available
S-EPMC4356709 | biostudies-literature
UnknownDiscovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRPα.
Not available
S-EPMC6748616 | biostudies-literature
TranscriptomicsExpression data from Control, AKT and RAS transduced cells
Mutations in both RAS and the PTEN/PIK3CA/AKT signaling module are found in the same human tumors. PIK3CA and AKT are downstream effectors of RAS, and the selective advantage conferred by mutation of two genes in the same pathway is unclear. Based on a comparative molecular analysis, we show that ac...
ORGANISM(S): Homo sapiens 
2013-03-19 | E-GEOD-45276 | biostudies-arrayexpress
TranscriptomicsGene expression in blood of mice with internal exposure to Cs-137
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled, it can expose the entire body for an extended period of time, potentially contributing to serious health consequences ranging from acute radiation syndrome to increased cancer...
ORGANISM(S): Mus musculus 
2014-08-31 | E-GEOD-52690 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD146 immunomagnetically enriched circulating endothelial cells (CECs) from healthy donors and patients with metastatic breast, colorectal, prostate, lung and renal cancer
Increased numbers of endothelial cells are observed in peripheral blood of cancer patients. These circulating endothelial cells (CECs) may contribute to the formation of blood vessels in the tumor or reflect vascular damage caused by treatment or tumor growth. Characterization of these cells may a...
ORGANISM(S): Homo sapiens 
2006-11-08 | E-MEXP-476 | biostudies-arrayexpress
UnknownInsertion mutagenesis of wca reduces acid and heat tolerance of enterohemorrhagic Escherichia coli O157:H7.
Not available
S-EPMC95261 | biostudies-literature
TranscriptomicsENCODE SUNY RNA Binding Protein Tiling Data for K562 and GM12878
RNA Binding Protein immunoprecipitation study for multiple target proteins in K562 & GM12878 cell lines as part of the ENCODE consortium. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2...
ORGANISM(S): Homo sapiens 
2012-09-24 | E-GEOD-40691 | biostudies-arrayexpress
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