Doyle M L ML - OmicsDI

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Unknown (117)
Transcriptomics (7)
Metabolomics (5)
Proteomics (4)
Genomics (1)

Organisms

Homo sapiens (3)
Mus musculus (2)
Populus x canadensis (1)
Staphylococcus aureus (1)
Arabidopsis thaliana (1)
Haemonchus contortus (1)
Saccharomyces cerevisiae (1)
Schizosaccharomyces pombe (1)

Repository

biostudies-arrayexpress (8)
MetaboLights (5)
pride (4)

Tissue

Erythrocyte (1)
Saccharomyces cerevisiae metabolite (1)

Disease

Colon mucinous adenocarcinoma (NCI Metathesaurus CL029553) in DiseaseLocation rectosigmoid colon has DiseaseStaging T3N2M1 (1)
Acute leukemia (1)
Haemonchiasis (1)

Technology Type

Mass spectrometry (5)
Mass Spectrometry (4)
Affinity purification coupled with mass spectrometry proteomics (1)
Bottom-up proteomics (1)
Gel-based experiment (1)
Shotgun proteomics (1)
Top-down proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (3)
Element AVITI (1)
Illumina HiSeq 2000 (1)
Exactive (Thermo Scientific) (1)
Gas Chromatography MS - positive (1)
LTQ Orbitrap Classic (Thermo Scientific) (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)

Publication Date

2025 (4)
2020 (2)
2026 (1)
2021 (1)
2014 (1)
2013 (1)
2009 (1)
2008 (1)
2007 (1)
2005 (1)
2022 (1)
2017 (1)
2019 (1)

CHEBI ID

CHEBI:1157 (2)
CHEBI:116314 (2)
CHEBI:137124 (2)
CHEBI:137246 (2)
CHEBI:15425 (2)
CHEBI:15428 (2)
CHEBI:15676 (2)
CHEBI:15727 (2)
CHEBI:15891 (2)
CHEBI:15978 (2)
CHEBI:16027 (2)
CHEBI:16040 (2)
CHEBI:16235 (2)
CHEBI:16335 (2)
CHEBI:16600 (2)
CHEBI:16695 (2)
CHEBI:16708 (2)
CHEBI:16737 (2)
CHEBI:16750 (2)
CHEBI:16919 (2)
CHEBI:17123 (2)
CHEBI:17138 (2)
CHEBI:17148 (2)
CHEBI:17151 (2)
CHEBI:17154 (2)
CHEBI:17261 (2)
CHEBI:17306 (2)
CHEBI:17368 (2)
CHEBI:17385 (2)
CHEBI:17509 (2)

Metabolite Name

2-Hydroxyethanesulfonate (2)
AMP (2)
N-(hexadecanoyl)-sphing-4-enine (2)
UMP (2)
(-)-Salsolinol (1)
(-)-jasmonoyl-L-phenylalanine (1)
(1-Ribosylimidazole)-4-acetate (1)
(2S,5S)-carboxymethylproline (1)
(5Z,7E)-(1S,3R)-23,24-dinor-9,10-seco-5,7,10(19)-cholatriene-1,3-diol (1)
(5Z,7E)-(1S,3R)-24,24-difluoro-26,27-dimethyl-9,10-seco-5,7,10(19)-cholestatrien-1,3,25-triol (1)
(5Z,7E)-(1S,3R)-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol (1)
(5Z,7E)-(3S)-3-hydroxy-9,10-seco-5,7,10(19)-cholatrien-24-oic acid (1)
(5Z,7E)-(3S)-6,19-ethano-9,10-seco-5(10),7-cholestadiene-3,25-diol (1)
(5Z,7E)-9,10-seco-5,7,10(19)-cholestatriene (1)
(R)-1-Aminopropan-2-ol (1)
(R)-3-Hydroxybutanoate (1)
(S)-1-Pyrroline-5-carboxylate (1)
(S)-2-Acetolactate (1)
(S)-3-Methyl-2-oxopentanoic acid (1)
(S)-Dihydroorotate (1)
(S)-Malate (1)
1',3'-Bis-[1-hexadecanoyl-2-(11Z-octadecenoyl)-sn-glycero-3-phospho]-sn-glycerol (1)
1,2-di-(9E-octadecenoyl)-sn-glycero-3-phosphoserine (1)
1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine (1)
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (1)
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine (1)
1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoserine (1)
1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine (1)
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-myo-inositol) (1)
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) (1)

Study type

Transcription profiling by array (5)
High-throughput sequencing (1)
ChIP-seq (1)
Methylation profiling by array (1)

Release Date

2021 (15)
2022 (12)
2023 (11)
2020 (11)
2018 (11)
2015 (10)
2024 (9)
2025 (7)
2016 (7)
2019 (6)
2026 (4)
2014 (4)
2017 (4)
2012 (4)
2013 (2)
2009 (2)
2008 (2)
2011 (2)
2007 (1)
2005 (1)

Lab affiliation

Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, USA. (1)
Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, Florida, 33136, USA (1)
Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria 3010, Australia (1)
Shankar Balasubramanian Lab University of Cambridge (1)

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Response of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer.

Objectives ELB-21 is a pyrrolo[2,1-c][1,4]benzodiazepine dimer with potent antistaphylococcal activity; it binds covalently to guanine residues on opposing strands of duplex DNA, interfering with regulatory proteins and transcription elongation in a sequence-selective manner. Transcriptional and pro...

ORGANISM(S): Staphylococcus aureus

2009-09-18 | E-BUGS-79 | biostudies-arrayexpress

Does Storage Post Sampling Influence the Stability of Sebum when used for Mass Spectrometry Metabolomics Analysis?

Sebum is a biofluid excreted by sebaceous glands in the skin. In recent years sebum has been shown to contain endogenous metabolites diagnostic of disease, with remarkable results for Parkinson’s Disease. Given that sebum sampling is facile and non-invasive, its potential for use in clinical bioc...

2025-07-15 | MTBLS7946 | MetaboLights

Study of poplar shoot apex methylome response to variations in soil water avaialbility

In a context of climate changes, water availability is expected to become a limiting factor for plant growth and to have an impact on forest health. In order to identify genes involved in shoot phenotypic plasticity in response to variations in water availability in trees, DNA methylation patterns w...

ORGANISM(S): Populus x canadensis

2014-01-01 | E-GEOD-46624 | biostudies-arrayexpress

Metabolomics of sebum reveals lipid dysregulation in Parkinson's disease

Parkinson's disease (PD) is a progressive neurodegenerative disorder, which is characterised by degeneration of distinct neuronal populations, including dopaminergic neurons of the substantia nigra. Here, we use a metabolomics profiling approach to identify changes to lipids in PD observed in sebum,...

2020-12-21 | MTBLS2266 | MetaboLights

Transcription profiling of Salmonella enterica serotype SL1344 wildtype, pSf-R27sfh and pSf-R27 at stationary and exponential growth phases, to investigate the role of the Sfh protein encoded by transmissible plasmids and involved in human typhoid

The Sfh protein is encoded by self-transmissible plasmids involved in human typhoid and is closely related to the global regulator H-NS. We have found that Sfh provides a stealth function that allows the plasmids to be transmitted to new bacterial hosts with minimal effects on their fitness. Introdu...

ORGANISM(S): Salmonella enterica serotype Typhimurium

2007-01-15 | E-SGRP-7 | biostudies-arrayexpress

The patatin-like protein PlpD forms novel structurally dynamic homodimers in the Pseudomonas aeruginosa outer membrane

Members of the Omp85 superfamily of outer membrane proteins (OMPs) found in Gram-negative bacteria, mitochondria and chloroplasts are characterized by a distinctive 16-stranded β-barrel transmembrane domain and at least one periplasmic POTRA domain. All previously studied Omp85 proteins promote c...

2025-12-08 | MTBLS9803 | MetaboLights

RNA-seq analysis of Arabidopsis thaliana cells treated with RN1 and 2,4-D

A PSB-D wild type Arabidopsis thaliana cell culture (Arabidopsis Biological Resource Center stock: CCL84840) was grown after subculturing for one week and divided into separate 10 mL samples for 24 h. Samples were then treated with 50 µM RubNeddin1 (RN1, Chembridge ID 6389186), 2,4-D, or an equal vo...

ORGANISM(S): Arabidopsis thaliana

2021-08-03 | E-MTAB-7761 | biostudies-arrayexpress

Frequency, Antimicrobial Susceptibility, and Molecular Characterization of Carbapenem-Resistant Enterobacterales Stratified by United States Census Divisions: Results From the INFORM Program (2018-2022).

Not available

S-EPMC11986335 | biostudies-literature

Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent

Leishmania donovani is the responsible agent for visceral leishmaniasis (VL) in the Indian subcontinent (ISC). The disease is lethal without treatment and causes 0.2 to 0.4 million cases each year. Recently, reports of VL in Nepalese hilly districts have increased as well as VL cases cau...

2022-09-15 | MTBLS1606 | MetaboLights

A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.