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ProteomicsMCU activity compensates for Complex I dysfunction
Co-immunoprecipitation experiments were performed in HEK293T cells in the absence and presence of Flag-tagged MCU and binding proteins were identified by tandem mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2022-03-10 | PXD018742 | Pride
Mitochondria Label-free Heart Co-ip Lc-ms/ms 
UnknownMitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Not available
S-EPMC9120069 | biostudies-literature
UnknownEnhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart.
Not available
S-EPMC11385101 | biostudies-literature
UnknownOccurrence of acute infarct-like myocarditis following COVID-19 vaccination: just an accidental co-incidence or rather vaccination-associated autoimmune myocarditis?
Not available
S-EPMC8325525 | biostudies-literature
UnknownA case series of double-chambered left ventricle detected by cardiovascular magnetic resonance.
Not available
S-EPMC10157389 | biostudies-literature
UnknownMachine Learning Multicenter Risk Model to Predict Right Ventricular Failure After Mechanical Circulatory Support: The STOP-RVF Score.
Not available
S-EPMC10831631 | biostudies-literature
UnknownPerm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1.
Not available
S-EPMC7310723 | biostudies-literature
UnknownClinical and functioning outcomes during the establishment phase of Ukraine's community mental health teams: a descriptive analysis.
Not available
S-EPMC12446188 | biostudies-literature
UnknownPERM1 regulates energy metabolism in the heart via ERRα/PGC-1α axis.
Not available
S-EPMC9676655 | biostudies-literature
ProteomicsDNA Damage in Macrophages Drives Immune Autoreactivity via Nuclear Antigen Presentation
Aging and DNA damage increase the risk of chronic inflammation and autoimmunity, yet their molecular underpinnings remain unclear. Here, we uncover a DNA damage-driven mechanism in macrophages that triggers immune autoreactivity. Using Er1Lyz2/- animals with a macrophage-specific DNA repair defect i...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-02 | PXD058775 | Pride
Dna damage  immunosenescence  antigen presentation  autophagy  immunopeptidomics  autoimmune responses  t-cell responses 
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