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MetabolomicsRabbit plasma metabolomic analysis of Nitroproston: a multi target natural prostaglandin based-drug (Untargeted study)
INTRODUCTION: Nitroproston® is a novel multi-target drug bearing natural prostaglandin E2 (PGE2) and nitric oxide (NO)-donating fragments for treatment of inflammatory and obstructive diseases (i.e. asthma and obstructive bronchitis). OBJECTIVES: To investigate the effects of Nitroproston® adm...
2019-08-27 | MTBLS727 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownProblems experienced by children from families with histories of substance misuse: An ABCD study®.
Not available
S-EPMC7750301 | biostudies-literature
TranscriptomicsRole of Aldoketoreductases and Other Doxorubicin Pharmacokinetic Genes in Doxorubicin Resistance, DNA binding, and Subcellular Localization
Objective: To assess the role of aldoketoreductases and other doxorubicin pharmacokinetic or pharmacogenomic genes in doxorubicin cytotoxicity, resistance, DNA binding activity, and subcellular localization, Methods: We conducted a whole genome microarray study to identify differences in betwee...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-27254 | biostudies-arrayexpress
UnknownComparison of timeline follow-back self-report and oral fluid testing to detect substance use in adult primary care patients.
Not available
S-EPMC7360056 | biostudies-literature
UnknownAdolescents' Use of Free Time and Associations with Substance Use from 1991 to 2019.
Not available
S-EPMC9746067 | biostudies-literature
UnknownOptimization of Methodologies to Study Freeze/Thaw Processes in Drug Substance Bottles.
Not available
S-EPMC11417747 | biostudies-literature
UnknownExamination of reward processing dysfunctions in the left dorsal striatum and other brain regions among psychiatric inpatients with substance use.
Not available
S-EPMC10923081 | biostudies-literature
UnknownExamining the efficacy of a computer facilitated HIV prevention tool in drug court.
Not available
S-EPMC5824990 | biostudies-literature
UnknownA developmental cascade model for early adolescent-onset substance use: the role of early childhood stress.
Not available
S-EPMC6519208 | biostudies-literature
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