Locally injected extracellular vesicles from iPS cell derived mesenchymal stem cells (iEVs) ameliorated long-term dry mouth, a common side effect of radiation therapy for head and neck cancer.
Natural compounds that can stimulate salivary secretion are of interest in developing treatments for xerostomia, the perception of a dry mouth, that affects between 10 and 30% of the adult and elderly population. Chemesthetic transient receptor potential (TRP) channels are expressed in the surface ...