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MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
ProteomicsEffect of acupuncture on tear proteomics in patients with video display terminal-related dry eye
In our study, the tear proteome was compared with identify possible mechanisms and biomarkers for predicting acupuncture effectiveness in VDT-related dry eye. The results showed that the Ocular Surface Disease Index (OSDI) scores were significantly different between the acupuncture group (AC group) ...
ORGANISM(S): Homo Sapiens 
PXD051759 |
MetabolomicsMolecular investigation of Tuscan sweet cherries sampled over three years: gene expression analysis coupled to metabolomics and proteomics

Sweet cherry (Prunus avium L.) is a stone fruit widely consumed and appreciated for its organoleptic properties, as well as its nutraceutical potential. We here investigated the characteristics of six non-commercial Tuscan varieties of sweet cherry maintained at the Regional Germplasm Ba...

2021-10-29 | MTBLS1803 | MetaboLights
MetabolomicsBiological Characteristics of SARS-CoV-2 Resistant Populations: A Cohort Comparison Study through Integrated Gut Microbiota Sequencing, Metabolomics and Proteomics

Objective: Most research reports on COVID-19 infections have focused on the correlation between the severity of the disease symptoms and immune deficits, while the mechanisms affecting the susceptibility to SARS-CoV-2 remain largely unknown. The study aimed to comprehensively analyze the differen...

2025-06-28 | MTBLS12654 | MetaboLights
ProteomicsCharacterization of Bovine Dry Secretions and their Proteome from the End of Lactation Through Day 21 of the Dry Period
The dry period in cow are critical to mammary health and the success of the next lactation. The expression of proteins the dry period progresses need to be characterized to provide information on involution and immune functions during the dry period. Total protein and lactoferrin concentrations ros...
ORGANISM(S): Bos taurus (Bovine) 
2020-05-20 | PXD017837 | Pride
Mastitis Mammary involution Proteome Dairy cow dry period Bovine dry secretions 
ProteomicsPROTEOMIC CHARACTERIZATION OF DRY BLOOD SPOTS OF HEALTHY WOMEN DURING SIMULATION THE MICROGRAVITY EFFECTS USING DRY IMMERSION
This study is unique in that it was the first time that it was the female response to microgravity simulated by 3-day dry immersion that was analyzed. The result of the choice of the object of research fell on dry blood spots, since the technique of capillary blood sampling is less invasive and allo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027654 | Pride
Human Healty human Mass-spectrometry Label-free Dry immersion 
ProteomicsHeterogeneity Assessment and Protein Pathway Prediction via Spatial Lipidomic and Proteomic Correlation: Advancing Dry Proteomics concept for Human Glioblastoma Prognosis
Prediction of proteins and associated biological pathways from lipid analyses via MALDI MSI is a pressing chal-lenge. We introduced "dry proteomics," using MALDI MSI to validate spatial localization of identified optimal clusters in lipid or protein imaging. Consistent cluster appearance across omic...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD054488 | Pride
Spatial proteomics Heterogeneity Dry proteomics Machine learn-ing Glioblastoma prognosis. Cluster estimation Maldi msi multi-omics 
UnknownPredicting Protein Pathways Associated to Tumor Heterogeneity by Correlating Spatial Lipidomics and Proteomics: The Dry Proteomic Concept.
Not available
S-EPMC11773152 | biostudies-literature
ProteomicsHuman Tear using MALDI-TOF-MS for Dry Eye syndrome
Tears are a biological fluid that has diagnostic potential for ocular diseases. Extracellular vesicles (EVs), wildly detected in various biofluids including tears, are nanoparticles released by living cells and considered as promising detection sources for non-invasive liquid biopsy. Understanding t...
ORGANISM(S): Homo sapiens (Human) 
2020-08-20 | PXD020217 | Pride
Human Maldi-tof ms Tear Dry eye syndrome Extracellular vesicles 
TranscriptomicsHeart-muscle expression ratios in pig obtained by 454-sequencing, iTRAQ-based proteomics and cDNA microarrays
The recent development within high-throughput technologies for expression profiling has allowed for parallel analysis of transcriptomes and proteomes in biological systems such as comparative analysis of transcript and protein levels of tissue regulated genes. Until now, such studies of have only in...
ORGANISM(S): Sus scrofa 
2009-01-22 | E-GEOD-10122 | biostudies-arrayexpress
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