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MetabolomicsMetabolomic assessment of acute cholestatic injuries induced by thioacetamide and by bile duct ligation, and the protective effects of Huang-Lian-Jie-Du-Decoction
Huang-Lian-Jie-Du-Decoction, a traditional Chinese formula, has been reported to protect liver from various injuries. Two cholestasis models of rats induced by thioacetamide and by bile duct ligation were established and treated with Huang-Lian-Jie-Du-Decoction. Nuclear Magnetic Resonance-based urin...
2016-06-08 | MTBLS149 | MetaboLights
UnknownTreatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.
Not available
S-EPMC5574319 | biostudies-literature
UnknownNoncoding RNAs in gastric cancer: Research progress and prospects.
Not available
S-EPMC4970485 | biostudies-literature
UnknownHepatic steatosis and pyroptosis are induced by the hepatitis B virus X protein via B56α-METTL3 interaction-mediated m6A modification of the NLRP3 mRNA.
Not available
S-EPMC12500908 | biostudies-literature
UnknownStepwise de novo establishment of inactive X chromosome architecture in early development.
Not available
S-EPMC12461747 | biostudies-literature
TranscriptomicsGene expression data from patients with colorectal cancer
Microarray analyses for the identification of differences in gene expression patterns have increased our understanding of the molecular genetic events in colorectal cancer. We used gene expression analysis data from recurrent and non-recurrent patients with colorectal cancer to identify differential...
ORGANISM(S): Homo sapiens 
2015-02-23 | E-GEOD-64857 | biostudies-arrayexpress
MetabolomicsDNA nanomachines reveal an adaptive energy mode in confinement-induced amoeboid migration powered by polarized mitochondrial distribution

Energy metabolism is highly interdependent with adaptive cell migration in vivo. Mechanical confinement is a critical physical cue that induces switchable migration modes of the mesenchymal-to-amoeboid transition (MAT). However, the energy states in distinct migration modes, especially a...

2024-03-25 | MTBLS9657 | MetaboLights
TranscriptomicsGeneration of Naïve Induced Pluripotent Stem Cells from Rhesus Monkey Fibroblasts
Conventional embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) derived from primates resemble mouse epiblast stem cells, raising an intriguing question regarding whether the naïve pluripotent state resembling mouse embryonic stem cells (mESCs) exists in primates and how to captur...
ORGANISM(S): Macaca mulatta 
2014-10-14 | E-GEOD-61420 | biostudies-arrayexpress
TranscriptomicsHuman Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
We generated induced human hepatocyte by transduction of several lineage specific transcription factors and analyzed the gene expression profile of generated hepatocytes and freshly isolated human hepatocytes through RNA sequencing. Global gene expression profile analysis
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-54066 | biostudies-arrayexpress
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
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