Ductal cells - OmicsDI

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Tissue

Cell culture (89)
Pancreas (29)
Epithelial cell (28)
Permanent cell line cell (26)
Pancreatic ductal cell (22)
Pancreatic ductal adenocarcinoma cell (8)
Epithelial cell of pancreas (6)
Pancreatic ductal adenocarcinoma cell line (6)
Epithelium of pancreatic duct (5)
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Breast (3)
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Pancreatic duct (3)
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Blood (2)
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Primary cell (2)
Heart (1)
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Pancreatic ductal adenocarcinoma tissues and cells (1)

Disease

Pancreatic ductal adenocarcinoma (58)
Pancreatic cancer (25)
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Carcinoma (8)
Normal (6)
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Pancreatic carcinoma (5)
Invasive ductal carcinoma (4)
Colorectal Neoplasms (4)
Infiltrating ductal carcinoma (3)
Cholangiocarcinoma (3)
Breast carcinoma (2)
Ductal breast cancer (2)
Adenocarcinoma (2)
Disease free (2)
Ductal carcinoma in situ (1)
Benign tumor (1)
Perineural invasion (1)
Invasive Ductal Carcinoma (1)
Chronic pancreatitis (1)
Adenocarcinoma (1)
Lymphoma (1)
Cholangiocarcinoma (1)
Cancer (1)
Breast ductal adenoma (1)
Breast ductal carcinoma (1)
Burkitt lymphoma (1)
Colon cancer (1)
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Technology Type

Mass Spectrometry (180)
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Instrument Platform

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Publication Date

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2008 (21)
2007 (12)
2006 (5)
2005 (2)

CHEBI ID

CHEBI:15354 (5)
CHEBI:16919 (4)
CHEBI:17368 (4)
CHEBI:17822 (3)
CHEBI:16709 (3)
CHEBI:18132 (3)
CHEBI:16856 (3)
CHEBI:18237 (3)
CHEBI:22660 (3)
CHEBI:27570 (3)
CHEBI:15676 (3)
CHEBI:15956 (3)
CHEBI:16750 (3)
CHEBI:25017 (3)
CHEBI:15428 (3)
CHEBI:6650 (3)
CHEBI:17015 (3)
CHEBI:17154 (3)
CHEBI:16393 (3)
CHEBI:7916 (3)
CHEBI:28946 (3)
CHEBI:16449 (3)
CHEBI:24813 (3)
CHEBI:17385 (3)
CHEBI:29016 (3)
CHEBI:18012 (3)
CHEBI:30887 (3)
CHEBI:78320 (3)
CHEBI:17895 (3)
CHEBI:17295 (3)

Metabolite Name

Choline (4)
Serine (3)
Hypoxanthine (3)
S-(1,2-dicarboxyethyl)glutathione (2)
Malate (2)
Histidine (2)
Glutamate (2)
Aspartate (2)
Glycine (2)
Allantoin (2)
Creatine (2)
Niacinamide (2)
Pyridoxine (2)
Arginine (2)
Lactate (2)
Alanine (2)
Succinate (2)
L-Tryptophan (2)
Glutamine (2)
Glucose (2)
Fumarate (2)
Glycerophosphocholine (2)
L-Tyrosine (2)
Bicyclo-PGE2 (1)
5-HYDROXY-L-TRYPTOPHAN (1)
N-METHYL-L-GLUTAMATE (1)
6-DEOXY-L-GALACTOSE (1)
O-ACETYL-L-CARNITINE (1)
2'-DEOXYCYTIDINE 5'-DIPHOSPHATE (1)
Hydroxyphenanthrene (1)

First Public Date

2025 (251)
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2022 (117)
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2021 (90)
2014 (90)
2019 (56)
2017 (53)
2018 (37)
2015 (28)
2016 (22)
2013 (3)

Modelling Approach

Ordinary differential equation model (1)

Study status

Recruiting (4)
Terminated (2)
Completed (2)
Active, not recruiting (1)
Not yet recruiting (1)

Lab affiliation

Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (5)
Centre for Cancer Cell & Molecular Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. (5)
Lineberger Comprehensive Cancer Center at UNC Chapel Hill (4)
Daglig leder, PROMEC Institutt for klinisk og molekylær medisin lars.hagen@ntnu.no 73598508 72573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 (3)
Department of Biochemistry and Molecular Biology and the Biomedicine Discovery Institute; Monash University; Clayton 3800; Victoria; Australia (3)
University of Manchester (3)
Cancer Research UK Manchester Institute (2)
Centre for Cancer Cell & Molecular Biology Barts Cancer Institute Queen Mary University of London Charterhouse Square London EC1M 6BQ U.K. (2)
Cold Spring Harbor Laboratory (2)
General Manager of PROMEC Department of Clinical and Molecular Medicine +4773598508 +4772573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 Norway (2)
Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) (2)
Professor and Vice Chairman for Research Department of Biochemistry and Molecular Genetics Co-Leader, Experimental Therapeutics Program UAB O'Neal Comprehensive Cancer Center Hugh Kaul Human Genetics Building, Kaul 504A The University of Alabama at Birmingham Birmingham, Alabama (2)
State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, China (2)
Tianjin Medical University Cancer Institute and Hospital (2)
Translational Genomics Research Institute (2)
Turku Centre for Biotechnology University of Turku and Åbo Akademi University Finland (2)
1 Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2 Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3 Taikang Center for Life and Medical Sciences of Wuhan University (1)
1. Division of Experimental Medicine, McGill University, Montreal, QC 2. Segal Cancer Proteomics Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC 3. Department of Pathology, Segal Cancer Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC 4. Segal Cancer Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC 5. Department of Oncology, McGill University, Montreal, QC (1)
1Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3Taikang Center for Life and Medical Sciences of Wuhan University (1)
1¬ MRM Proteomics Inc, Montreal, Quebec, Canada 2 Segal Cancer Proteomics Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada 3 Gerald Bronfman Department of Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada (1)
733 N. Broadway Miller Research Building room 527 Johns Hopkins University Baltimore, MD 21205 (1)
Abbvie Bioresearch Center (1)
Acting Head of Proteomics (1)
Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (1)
AmsterdamUMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, The Netherlands (1)
Assistant Professor of Biological Sciences Augusta University C2014 Science Hall 2500 Walton Way, Augusta-GA (1)
Assistant Professor of Pediatrics Assistant Professor of Pharmacology & Toxicology Indiana University School of Medicine (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) School of Life Sciences Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY Bavarian Center for Biomolecular Mass Spectrometry Technische Universität München Gregor-Mendel-Straße 4 85354 Freising DEUTSCHLAND / GERMANY (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Biotech Research and Innovation Centre (BRIC), University of Copenhagen (UCPH), Copenhagen, Denmark (1)

Keyword

Vaccines (2)
GDC-0449 (1)
Solid Organ Cancers (1)
Adjuvants, Vaccine (1)
Natural History (1)
Solid Organ Cancer (1)
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Imiquimod (1)
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Molgramostim (1)
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Fibroblast Activation Protein (1)
Fibroblast Activation Protein Inhibitor (1)
FAPI (1)
Durvalumab (1)
Pembrolizumab (1)

IsPrivate

False (1)

Classification

bacteria (1)

Modification

2x(15)N labeled L-lysine (2)
4x(15)N labeled L-arginine (2)

Study type

Transcription profiling by array (230)
RNA-seq of coding RNA (53)
Comparative genomic hybridization by array (17)
ChIP-seq (14)
RNA-seq of coding RNA from single cells (9)
Interventional (9)
Methylation profiling by array (8)
RNA-seq of non coding RNA (5)
Genotyping by array (4)
DNA-seq (4)
Cell line - High-throughput sequencing (3)
Unknown experiment type (2)
ChIP-chip by array (2)
Spatial transcriptomics by high-throughput sequencing (2)
Methylation profiling by high throughput sequencing (2)
One-color microarray (1)
Transcription profiling by RT-PCR (1)
Bisulfite-seq (1)
ATAC-seq (1)
Other (1)
MicroRNA profiling by array (1)
RNA-seq of total RNA (1)
Observational (1)

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2007 (28)
2006 (13)
2005 (10)
2003 (5)
2004 (4)
2002 (3)
2001 (2)
2000 (2)
1999 (1)

Location

United States (7)
United Kingdom (1)
France (1)

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Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

Cross-talk among downstream regulatory networks of genome mutations has been the major hypothetical mechanism underlying poor prognosis and low-responsive rates for targeted therapy of pancreatic ductal adenocarcinoma (PDAC). By applying a causal inference-based mutation-upstream-of-the-metabolom...

2025-10-13 | MTBLS13127 | MetaboLights

Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

2025-10-13 | MTBLS13116 | MetaboLights

Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

2025-10-13 | MTBLS13111 | MetaboLights

Metabolic reprogramming is an initial step in pancreatic carcinogenesis that can be targeted to inhibit acinar-to-ductal metaplasia

Metabolic reprogramming is a hallmark of cancer and is crucial for cancer progression, making it an attractive therapeutic target. Understanding the role of metabolic reprogramming in cancer initiation could help identify prevention strategies. To address this, we investigated metabolism during a...

2024-05-31 | MTBLS9772 | MetaboLights

Transcription profiling of human pancreatic ductal cells from pancreatic ductal carcinoma patients and healthy subjects

RNA was purified from pancreatic ductal cells, and was subjected to microarray experiments with HGU133 A&B arrays.

ORGANISM(S): Homo sapiens

2007-08-04 | E-GEOD-1542 | biostudies-arrayexpress

Gene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast

Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...

ORGANISM(S): Homo sapiens

2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress

Ductal Carcinoma Progression

To obtain insight into the molecular basis of ductal carcinoma in situ (DCIS) and its progression by infiltrating surrounding tissue, we have performed cellular-based gene expression analysis of pure DCIS and DCIS with co-existing invasive ductal carcinoma (IDC) and compared the histological and mol...

ORGANISM(S): Homo sapiens

2008-04-04 | E-GEOD-11042 | biostudies-arrayexpress

Transcription profiling of microdissected human microdissected pancreas ductal adenocarcinoma vs. microdissected normal duct cells

Comparison of the gene expression of microdissected pancreas ductal adenocarcinoma to microdissected normal duct cells

ORGANISM(S): Homo sapiens

2006-12-24 | E-MEXP-950 | biostudies-arrayexpress

Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer

This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive...

ORGANISM(S): Homo sapiens

2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress

KSN01_Proteome_CellLine: Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H

Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H

ORGANISM(S): Homo Sapiens (human)

2020-12-15 | PXD010107 | JPOST Repository

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