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TranscriptomicsHuman embryonic stem cells as a tool to study hepatocyte differentiation
The availability of pluripotent stem cells offers the possibility of using such cells to model hepatic disease and development. With this in mind, we previously established a protocol that facilitates the differentiation of both human embryonic stem cells and induced pluritpotent cells into cells wi...
ORGANISM(S): Homo sapiens 
2011-08-21 | E-GEOD-25417 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human hepatic cells derived from foreskin fibroblast cell line and from embryonic stem cells.
Reprogrammed somatic cells offer a valuable source of pluripotent cells that have the potential to differentiate into many cells types and provide a new tool for regenerative medicine. In the present study we differentiated induced pluripotent stem cells (iPS cells) into hepatic cells. We first show...
ORGANISM(S): Homo sapiens 
2009-08-07 | E-GEOD-14897 | biostudies-arrayexpress
TranscriptomicsThe transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism
Here we report that the transcription factor cyclic AMP–responsive element–binding protein H (CREB-H, encoded by CREB3L3) is required for the maintenance of normal plasma triglyceride concentrations. CREB-H–deficient mice showed hypertriglyceridemia secondary to inefficient triglyceride clearance ca...
ORGANISM(S): Mus musculus 
2011-06-04 | E-GEOD-29643 | biostudies-arrayexpress
TranscriptomicsExpression data from ileum of inducible intestine-specific GATA6 knockout mice
GATA6 is a transcription factor involved in the differentiation of intestinal epithelial cells into differentiated absorptive epithelial cells. GATA6 is expressed in all segments of the small intestine. We examined the impact of deleting GATA6 from intestinal epithelial cells of the adult ileum 6-8...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-22416 | biostudies-arrayexpress
GenomicsMapping of cohesin, CTCF and a collection of tissue-specific and ubiquitous transcriptional regulators using ChIP-seq in primary wild type and Rad21-cohesin haploinsufficient mouse liver
Mapping of cohesin, CTCF and a collection of tissue-specific and ubiquitous transcriptional regulators using ChIP-seq in primary mouse liver. The following antibodies were used: CTCF (upstate, 07729), STAG1 (abcam, ab4457), STAG2 (abcam, 4464), RAD21 (abcam, ab992), CEBPA (santa cruz, sc9314), HNF4A...
ORGANISM(S): Mus musculus 
2012-06-22 | E-MTAB-941 | biostudies-arrayexpress
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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