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TranscriptomicsRoles for microRNAs, miR-93 and miR-130b, and TP53INP1 tumor suppressor in cell growth dysregulation by HTLV-1
This is to study the role of miRNAs in human T-cell leukemia virus-1, HTLV-1. In this study, we profiled the miRNA expression in virus transformed human cell lines and primary peripheral blood mononuclear cells (PBMCs) from Adult-T cell leukemia (ATL) patients using the RNA-primed, array-based Kleno...
ORGANISM(S): Homo sapiens 
2008-06-06 | E-GEOD-11577 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomic profiling of patient-derived pancreatic ductal adenocarcinoma primary cell cultures
Single-cell transcriptomic dataset comprising 41 patient-derived cell cultures (PDCs) established from pancreatic ductal adenocarcinoma (PDAC). The dataset was generated using Evercode™ technology with the Whole Transcriptome v2 kit (Parse Biosciences, ECW02130), based on Split Pool Ligation-based T...
ORGANISM(S): Homo sapiens 
2026-04-15 | E-MTAB-16856 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis Predicts Clinical Outcome and Sensitivity to Anticancer Drugs of patients with a Pancreatic Adenocarcinoma
A major impediment to the effective treatment of patients with PDAC (Pancreatic Ductal Adenocarcinoma) is the molecular heterogeneity of the disease, which is reflected in an equally diverse pattern of clinical responses to therapy. We developed an efficient strategy in which PDAC samples from 17 co...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-55513 | biostudies-arrayexpress
TranscriptomicsSlit2/Robo axis is mandatory for neural remodeling in pancreatic cancer.
Pancreatic Ductal Adenocarcinoma (PDA) is a critical health issue in cancer field with little new therapeutic options. Several evidences support an implication of intra-tumoral microenvironment (stroma) on PDA progression. However, its contribution to the role of neuroplastic changes within pathophy...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-50570 | biostudies-arrayexpress
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