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DUX domain-dependent chromatin accessibility of DUX binding sites
We report both DUX4 and Dux toxicity depend upon their ability to bind DNA and activate transcription. Chromatin immunoprecipitation of V5 epitope tagged human DUX4 and mouse Dux was performed in human myoblasts was analyzed using ChIP-Seq to identify their subsequent binding sites. We found that DU...
ORGANISM(S): Homo sapiens 
We report the RNA-seq experiments performed in human myoblasts transfected with human DUX4 and mouse Dux. Comparison of genes up- and down-regulated by DUX4 and Dux in human myoblasts to identify pathways similiarly regulated by both transcription factors.
ORGANISM(S): Homo sapiens 
RNA-sequencing in mESCs with overexpression of mCherry-tagged DUX and DUX domain derivatives
DUX
The process of iPSC reprogramming involves various critical events such as somatic gene shutdown, mesenchymal-epithelial transition (MET), metabolism reprogramming, and epigenetic rewiring. These events interweave and influence each other leading to the formation of the iPSC reprogramming network, t...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD043547 | Pride
Single cell RNA-seq Analysis of Wild Type(WT), Dux knockout(KO) and Dux overexpression(OE) embryos
Time point RNA-seq of Dux over expression samples reveals different transcriptomes of Dux induction in mESC
RNAseq of DUX KO mouse 2-cell embryos
CRISPRa-mediated entanglement of the Dux-MERVL axis
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