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TranscriptomicsPotentiation of glucocorticoid signaling by chloroquine via inhibition of lysosomes
Anti-malaria drug chloroquine has been used as an anti-inflammatory agent for treating systemic lupus erythematosus and rheumatoid arthritis, without clear mechanism of action. Here we report that chloroquine potently inhibits the expression of proinflammatory cytokines through transrepression of g...
ORGANISM(S): Homo sapiens 
2012-01-18 | E-GEOD-24579 | biostudies-arrayexpress
TranscriptomicsSomatic Mutation Screen of Clear Cell RCC I
Systematic somatic mutation screening of 4000 genes in human clear cell renal cell carcinoma. Information on corresponding somatic mutations in each sample can be found at http://www.sanger.ac.uk/genetics/CGP/Studies/. These samples were run at a different facility than VARI - scmmlab.com Correlat...
ORGANISM(S): Homo sapiens 
2010-01-04 | E-GEOD-17816 | biostudies-arrayexpress
TranscriptomicsSomatic Mutation Screen of Clear Cell RCC II
Systematic somatic mutation screening of 4000 genes in human clear cell renal cell carcinoma. Information on corresponding somatic mutations in each sample can be found at http://www.sanger.ac.uk/genetics/CGP/Studies/. Correlating gene expression profiling with mutational status
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-17818 | biostudies-arrayexpress
TranscriptomicsSomatic Mutation Screen of Clear Cell RCC
This SuperSeries is composed of the following subset Series: GSE17816: Somatic Mutation Screen of Clear Cell RCC I GSE17818: Somatic Mutation Screen of Clear Cell RCC II Systematic somatic mutation screening of 4000 genes in human clear cell renal cell carcinoma. Information on corresponding somatic...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-17895 | biostudies-arrayexpress
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