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ProteomicsThe impact of E2F/Dp inactivation on metabolism differs between muscles and fat body cells
We aim to determine the physiological impact of inactivating E2F in muscles and in adipose cells in vivo. To uncover the mechanism of action of E2F in each tissue we investigated the similarities between E2F-deficient tissues by comparing the proteomic profiles between muscles and fat cells. Our fin...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2021-02-11 | MSV000086854 | MassIVE
GenomicsThe genomic complexity of sporadic and inherited retinoblastoma with a matched orthotopic xenograft

Retinoblastoma is a pediatric cancer of the developing retina. All retinoblastomas are believed to initiate with biallelic inactivation of the RB1 gene. To identify subsequent genetic lesions in retinoblastoma, we performed whole genome sequencing of tumor and normal DNA of 4 children with retino...

phs000352.v1.p1 | EGA
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