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ProteomicsE-cadherin mechanotransduction activates EGFR/ERK signaling by inducing ligand shedding
The behavior of cells is governed by signals originating from their local environment, including mechanical forces that cells experience. Forces are transduced by mechanosensitive proteins, which can impinge on signaling cascades that are also activated by growth factor receptors upon ligand binding...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2025-11-18 | PXD052926 | Pride
Shedding Egfr ligand E-cadherin Force transduction 
ProteomicsE-cadherin mechanotransduction activates EGFR/ERK signaling by inducing ligand shedding
The behavior of cells is governed by signals originating from their local environment, including mechanical forces that cells experience. Forces are transduced by mechanosensitive proteins, which can impinge on signaling cascades that are also activated by growth factor receptors upon ligand binding...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2025-11-18 | PXD061223 | Pride
E-cadherin force transduction egfr ligand shedding 
GenomicsE-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding
E-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding
PRJNA1228921 | ENA
TranscriptomicsE-cadherin mechanotransduction activates EGFR-ERK signaling in epithelial monolayers by inducing ADAM-mediated ligand shedding
The behavior of cells is governed by signals originating from their local environment, including mechanical forces that cells experience. Forces are transduced by mechanosensitive proteins, which can impinge on signaling cascades that are also activated by growth factor receptors upon ligand binding...
ORGANISM(S): Canis lupus familiaris 
2025-05-21 | GSE290599 | GEO
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