Sort   by:  
 Page size 
ProteomicsE2F6 initiates stable epigenetic silencing of germline genes during embryonic development
In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes, however the molecular mechanisms of this specificity remain unclear. Here we demonstrate that the transcription factor E2F6, a member of the polycomb repressive complex 1.6 (PRC1.6), i...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-22 | PXD023974 | Pride
Embryonic stem cells Prc1.6 Dna methylation E2f6 
GenomicsRNA-seq data for E2F6 knockdown in Huh7 cells
RNA-seq data for E2F6 knockdown in Huh7 cells
PRJNA719120 | ENA
GenomicsRole of E2F6 in gene expression and DNA methylation during mouse development
Role of E2F6 in gene expression and DNA methylation during mouse development
PRJNA627179 | ENA
TranscriptomicsRNA-seq data for E2F6 knockdown in Huh7 cells
E2F6 plays oncogenic roles and in order to identify the molecular mechanism of E2F6 to promote tumorigenesis, RNA-seq was performed on Huh7 cells with or without E2F6.
ORGANISM(S): Homo sapiens 
2021-04-10 | GSE171319 | GEO
UnknownE2F6 associates with BRG1 in transcriptional regulation.
Not available
S-EPMC3474740 | biostudies-literature
UnknownE2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
Not available
S-EPMC2526686 | biostudies-literature
UnknownThe NRF-1/alpha-PAL transcription factor regulates human E2F6 promoter activity.
Not available
S-EPMC1133746 | biostudies-literature
UnknownA conserved E2F6-binding element in murine meiosis-specific gene promoters.
Not available
S-EPMC2715002 | biostudies-literature
TranscriptomicsRole of E2F6 in gene expression and DNA methylation during mouse development
In the mouse, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes in somatic cells, however the molecular mechanisms of this specificity remain unclear. Here we demonstrate that the transcription factor E2F6, a member of the polycomb repressive complex 1.6 (P...
ORGANISM(S): Mus musculus 
2021-04-26 | GSE149025 | GEO
UnknownE2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Not available
S-EPMC8195999 | biostudies-literature
Sort   by:  
 Page size