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TranscriptomicsComparison of primary neuroblastoma tumors and derivative early-passage cell lines using genome-wide SNP array analysis
Stromal contamination is one of the major confounding factors in the analysis of primary solid tumor samples by single nucleotide polymorphism (SNP) arrays. As we propose to employ genome-wide SNP microarray analysis as a diagnostic platform for neuroblastoma, the sensitivity, specificity, and accur...
ORGANISM(S): Homo sapiens 
2009-01-31 | E-GEOD-14656 | biostudies-arrayexpress
ProteomicsImpaired presynaptic proteostasis in the initial stages of amyloid beta proteotoxicity
Compromised protein homeostasis underlies accumulation of plaques and tangles in Alzheimers disease (AD); however, little is known about the early mechanisms that contribute to this accumulation. To objectively assess the impaired protein turnover at early stages of amyloid beta (Abeta) proteotoxic...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-24 | MSV000085004 | MassIVE
ProteomicsHs_MitoticExit_Phos_Silac_IT
Global phosphoproteomic mapping of early mitotic exit in human hela cells, ITCID
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005294 | PeptideAtlas
ProteomicsHs_MitoticExit_Phos_Silac_HCD
Global phosphoproteomic mapping of early mitotic exit in human hela cells, HCD
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005254 | PeptideAtlas
ProteomicsAlzheimer's disease proteomics
This project aims to determine how the brain proteome is remodeled in Alzheimer's disease (AD). AD is pathologically characterized by an accumulation of insoluble aggregates composed of Abeta peptides in the brain and is clinically characterized by progressive memory impairment. While the precise pa...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-12-19 | MSV000080431 | MassIVE
TranscriptomicsPseudomonas aeruginosa lasR mutants in young cystic fibrosis patients
Pseudomonas aeruginosa undergoes genetic change during chronic infection of the airways of cystic fibrosis (CF) patients. One common change is mutation of lasR. LasR is a transcriptional regulator that responds to one of the quorum sensing signals in P. aeruginosa, and regulates acute virulence fa...
ORGANISM(S): Pseudomonas aeruginosa 
2010-06-30 | E-GEOD-5560 | biostudies-arrayexpress
UnknownInternal state configures olfactory behavior and early sensory processing in Drosophila larvae.
Not available
S-EPMC7775770 | biostudies-literature
UnknownTreatment-resistant psychotic symptoms and early-onset dementia: A case report of the 3q29 deletion syndrome.
Not available
S-EPMC11491492 | biostudies-literature
TranscriptomicsTranscription profiling by high throughput sequencing of Schizosaccharomyces pombe transcriptome during both proliferation and quiescence
Data on absolute molecule numbers are rare but will empower the modeling, understanding and comparison of cellular functions and biological systems. We quantified transcriptomes and proteomes in fission yeast during both proliferation and quiescence. This rich resource provides the first comprehensi...
ORGANISM(S): Schizosaccharomyces pombe 
2012-10-26 | E-MTAB-1154 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe
Polyadenylation of pre-mRNAs, a critical step in eukaryotic gene expression, is mediated by cis elements, collectively called the polyadenylation signal. Genome-wide analysis of such polyadenylation signals was missing in fission yeast, which is an important model organism. We demonstrate that the c...
ORGANISM(S): Schizosaccharomyces pombe 
2013-09-01 | E-MTAB-1824 | biostudies-arrayexpress
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