Sort   by:  
 Page size 
MetabolomicsPolymicrobial detection and metabolomics in saliva of children with early childhood caries

Cariogenic microorganisms as well as salivary metabolic status in early childhood caries (ECC) have been reported to differ from that in adult caries. The main aim of this study was to identify specific microbial species and salivary metabolites in children with ECC using species-specific qPCR an...

2024-11-12 | MTBLS10890 | MetaboLights
MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
MetabolomicsCoupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights
MetabolomicsA blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights
MetabolomicsMetabolomics Insights in Early Childhood Caries
Dental caries is characterized by a dysbiotic shift at the biofilm-tooth surface interface, yet comprehensive biochemical characterizations of the biofilm are scant. We used metabolomics to identify biochemical features of the supragingival biofilm associated with early childhood caries (ECC) preval...
2021-01-29 | MTBLS2215 | MetaboLights
MetabolomicsMetabolomics of Solanum lycopersicum infected by Phytophthora infestans leads to Late blight detection and reveals metabolic differences in infection times
Tomato crops suffer attacks of various pathogens that cause large production losses. Late blight caused by Phytophthora infestans is a devastating disease in tomatoes because of its difficultly to control. Here, we applied metabolomics based on liquid chromatography–mass spectrometry (LC-MS) and met...
2019-01-24 | MTBLS618 | MetaboLights
MetabolomicsUntargeted serum metabolomic profiling for early detection of Schistosoma mekongi infection in mouse model
Not available
ORGANISM(S): Mus musculus 
ST002158 | MetabolomicsWorkbench
MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
MetabolomicsEarly-life social experiences remodel hippocampal glycerophospholipid metabolism linked to adult memory

Early-life experiences profoundly shape brain development and long-term cognition. Environmental enrichment (EE) and social isolation (SI) represent opposing forms of stimulation and deprivation, yet the metabolic mechanisms connecting these conditions to cognitive outcomes remain poorly defined....

2025-12-04 | MTBLS13454 | MetaboLights
MetabolomicsPlasma Metabolomics Profiling of 580 Patients from the Weill Cornell Medicine Early Detection Research Network Prostate Cancer Cohort
Not available
ORGANISM(S): Homo sapiens 
ST002498 | MetabolomicsWorkbench
Sort   by:  
 Page size