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MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
MetabolomicsComprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation
In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...
2025-08-27 | MTBLS12325 | MetaboLights
MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsIntegrative multi-omics analysis of rumen development in early-life yaks
This study investigates the developmental changes in the rumen of early-life yaks using integrative metagenomics, metabolomics, histology, fermentation profiling, and single-cell transcriptomics. Rumen fluid and epithelial tissue samples collected from yaks at 1, 6, and 12 months of age were analyze...
2026-04-21 | MTBLS14340 | MetaboLights
MetabolomicsChanges in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth – Three Phases in Early Lactation and Progressive Individual Differences
Ursids (bears) in general, and giant pandas in particular, are highly altricial at birth. The components of bear milks and their changes with time may be uniquely adapted to nourish relatively immature neonates, protect them from pathogens, and support the maturation of neonatal digestive physiology...
2015-03-31 | MTBLS165 | MetaboLights
TranscriptomicsSAGE in Cultured Murine COC During Early Maturation
In cultured cumulus oocyte complexes (COC) FSH induces gene transcription required for germinal vesicle breakdown (GVBD). Experiments were performed to determine the critical period when gene transcription is required for GVBD and identify candidate mRNAs involved. Experiment I: murine COC were cult...
ORGANISM(S): Mus musculus 
2006-08-31 | E-GEOD-5568 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of soybean seeds containing early maturation stage embryos
We microdissected each compartment from 8-micron paraffin sections using the Leica LMD6000 system to identify all genes active in different compartments of a soybean seed containing a early maturation-stage embryo. Experiment Overall Design: early maturation-stage seed compartments were isolated usi...
ORGANISM(S): Glycine max 
2008-06-17 | E-GEOD-8112 | biostudies-arrayexpress
GenomicsMethylation Changes in Soybean Early Maturation Seed Parts
What methylation changes are occurring in different parts of early maturation stage seed largely remains unknown. To uncover the possible role of DNA methylation in different parts of early maturation stage seed, we characterized the methylome of seed coats,cotyledons, and the embryonic seed axis us...
ORGANISM(S): Glycine max 
2012-05-11 | E-GEOD-37895 | biostudies-arrayexpress
GenomicsMethylation Changes in Soybean Early Maturation Seed Compartments Using LCM
What methylation changes are occurring in different compartments of early maturation stage seed largely remains unknown. To uncover the possible role of DNA methylation in different compartments of early maturation stage seed, we characterized the methylome of two major compartments in embryonic cot...
ORGANISM(S): Glycine max 
2012-05-11 | E-GEOD-37893 | biostudies-arrayexpress
ProteomicsTMT proteomic analysis of tropical quinoa (Chenopodium quinoa willd.) seeds during maturation
Many limitation factors, such as seed pre-harvest sprouting, bitter saponin e.c., greatly restricts quinoa production and popularity. To solves these problems, the underlying mechanism of seed maturation in quinoa was required. In this study, morphological observation, TMT proteomics and parallel re...
ORGANISM(S): Chenopodium quinoa 
2022-10-19 | PXD034885 | Pride
Quinoa Seed maturation Regulation mechanism Tmt proteomic 
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