Sort   by:  
 Page size 
UnknownThe Placental Innate Immune System Is Altered in Early-Onset Preeclampsia, but Not in Late-Onset Preeclampsia.
Preeclampsia is a severe placenta-related pregnancy disorder that is generally divided into two subtypes named early-onset preeclampsia (onset <34 weeks of gestation), and late-onset preeclampsia (onset ≥34 weeks of gestation), with distinct pathophysiological origins. Both forms of preeclampsia hav...
S-EPMC8724430 | biostudies-literature
UnknownEarly-onset Preeclampsia in Lupus Pregnancy.

Background

Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that occurs during childbearing years and has been associated with preeclampsia. However, little is known about preeclampsia of early onset, which is associated with severe adverse maternal and perinatal o...
S-EPMC5624307 | biostudies-literature
UnknownHeart rate variability and baroreceptor reflex sensitivity in early- versus late-onset preeclampsia.

Objective

To determine whether there are differences in autonomic nervous system function in early- versus late-onset preeclampsia.

Methods

Matched case-control study. Cases were defined as singleton pregnancies with preeclampsia at < 34+0 weeks of gestation (early-onset preeclampsia)...
S-EPMC5650147 | biostudies-literature
UnknownDistinct placental molecular processes associated with early-onset and late-onset preeclampsia.
Background: Patients with preeclampsia display a spectrum of onset time and severity of clinical presentation, yet the underlying molecular bases for the early-onset and late-onset clinical subtypes are not known. Although several transcriptome studies have been done on placentae from PE pati...
S-EPMC7978310 | biostudies-literature
UnknownMaternal circulating concentrations of soluble Fas and Elabela in early- and late-onset preeclampsia.

Objective

The Fas/Fas ligand (FASL) system and Elabela-apelin receptor signaling pathways are implicated in the pathophysiology of preeclampsia. The aim of the current study was to investigate whether a model combining the measurement of sFas and Elabela in the maternal circulation may serve...
S-EPMC10544759 | biostudies-literature
UnknownThe common single-nucleotide polymorphism rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.
Preeclampsia, characterized by hypertension and proteinuria, remains a leading cause of maternal morbidity and mortality. Recently, a genome-wide association study (GWAS) identified the single-nucleotide polymorphism, rs2681472, as a new hypertension susceptibility genetic variant. The purpose of th...
S-EPMC4212332 | biostudies-literature
UnknownMaternal cardiovascular-related single nucleotide polymorphisms, genes, and pathways associated with early-onset preeclampsia.

Introduction

Preeclampsia is a medical condition complicated with hypertension and proteinuria during pregnancy. While preeclampsia affects approximately 5% of pregnancies, it remains without a cure. In addition, women who had preeclampsia during pregnancy have been reported to have an incre...
S-EPMC6762142 | biostudies-literature
UnknownEarly Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion.
Background The endothelial glycocalyx is a vasoprotective barrier between the blood and endothelium. We hypothesized that glycocalyx degradation is present in preeclampsia, a pregnancy-specific hypertensive disorder characterized by endothelial dysfunction and activation. Methods and Results We exam...
S-EPMC6405679 | biostudies-literature
UnknownAssessment of the fullPIERS Risk Prediction Model in Women With Early-Onset Preeclampsia.
Early-onset preeclampsia is associated with severe maternal and perinatal complications. The fullPIERS model (Preeclampsia Integrated Estimate of Risk) showed both internal and external validities for predicting adverse maternal outcomes within 48 hours for women admitted with preeclampsia at any ge...
S-EPMC5865495 | biostudies-literature
UnknownIs artificial endometrial preparation more associated with early-onset or late-onset preeclampsia after frozen embryo transfer?

Purpose

To explore whether the risks of early- or late-onset preeclampsia vary among frozen embryo transfer (FET) with different regimens for endometrial preparation and fresh embryo transfer (FreET).

Methods

We retrospectively included a total of 24129 women who achieved singleton de...
S-EPMC10239427 | biostudies-literature
Sort   by:  
 Page size