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TranscriptomicsIdentifying Sites Bound by Epstein Barr Nuclear Antigen 1 (EBNA1) in the Human Genome
Epstein-Barr virus (EBV) is a ubiquitous gammaherpes virus that establishes a life-long latency in over 90% of the world's population. Epstein Barr Nuclear Antigen 1, EBNA1, is the only viral protein consistently detected in all viral latency programs, as well as in all forms of EBV-associated malig...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-13315 | biostudies-arrayexpress
GenomicsGenome-Wide Analysis of Host-Chromosome Binding Sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)
The Epstein-Barr Virus (EBV) Nuclear Antigen 1 (EBNA1) protein is required for the establishment of EBV latent infection in proliferating B-lymphocytes. EBNA1 is a multifunctional DNA-binding protein that stimulates DNA replication at the viral origin of plasmid replication (OriP), regulates transc...
ORGANISM(S): Homo sapiens 
2011-07-16 | E-GEOD-30709 | biostudies-arrayexpress
TranscriptomicsIdentification of MEF2B, EBF1, and IL6R as chromosome bound targets of EBNA1 essential for EBV infected B-lymphocyte survival
EBNA1 is the EBV-encoded nuclear antigen required for viral episome maintenance during latency. EBNA1 is a sequence specific DNA binding protein with high affinity binding sites for the viral genome, especially OriP. EBNA1 can also bind sequence specifically to a large number of sites in the host ...
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-73887 | biostudies-arrayexpress
ProteomicsThe B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM
This data set contains the mass spectrometry raw files for the paper The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM. In multiple sclerosis (MS) intrathecal B lymphocytes are directly involved in inflammation and secrete oligoclonal immunoglobulin. Ho...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-11 | MSV000086842 | MassIVE
GenomicsUSP7 inhibitors disrupt EBNA1 interactome and EBV tumorigenesis
USP7 inhibitors disrupt EBNA1 interactome and EBV tumorigenesis
PRJNA1200707 | ENA
GenomicsRIP-Seq of EBNA1 from EBV in HEK293T cells
RIP-Seq of EBNA1 from EBV in HEK293T cells
PRJNA421443 | ENA
ProteomicsAntibodies against the mono-methylated Arginine-Glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 1 (EBNA1) identify potential cellular proteins targeted in viral transformation
The viral nuclear antigen 1 (EBNA1) of Epstein Barr (EBV) features two functionally redundant Arginine-Glycine (RG) repeats that contain symmetrically and asymmetrically di-methylated (SDMA/ADMA) and also mono-methylated (MMA) Arginine residues. We generated mouse monoclonal antibodies against the m...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 4 
2025-03-05 | PXD051181 | Pride
Epstein-barr virus Arginine-methylation Ebna1 Mono-methyl-arginine 
GenomicsEBNA1 SUMOylation by PIAS1 Suppresses EBV Lytic Replication and Enhances Episome Maintenance
EBNA1 SUMOylation by PIAS1 Suppresses EBV Lytic Replication and Enhances Episome Maintenance
PRJNA1310941 | ENA
GenomicsGlobal alternative RNA splicing analysis of Epstein-Barr Virus EBNA1-regulated cells
Global alternative RNA splicing analysis of Epstein-Barr Virus EBNA1-regulated cells
PRJNA1203917 | ENA
TranscriptomicsEpstein-Barr Virus Nuclear Antigen 1 (EBNA1)
Expression of mRNAs in EBV-positive B-cell strains in the presence or absence of EBNA1 or a mutant of EBNA1 (ΔUR1-EBNA) that is unable to activate transcription.
ORGANISM(S): Homo sapiens 
2021-11-12 | GSE75198 | GEO
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