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TranscriptomicsPervasive TTP binding but selective target mRNA destabilization in the macrophage transcriptome [RNA-Seq]
Precise control of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. Parameters determining the specificity and extent of mRNA degradation within the entire inflammation-associated transcriptome remain incompletely understood. Using transcriptome-wide high...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-63467 | biostudies-arrayexpress
TranscriptomicsPervasive TTP binding but selective target mRNA destabilization in the macrophage transcriptome [PAR-iCLIP]
Precise control of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. Parameters determining the specificity and extent of mRNA degradation within the entire inflammation-associated transcriptome remain incompletely understood. Using transcriptome-wide high...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-63466 | biostudies-arrayexpress
TranscriptomicsPervasive TTP binding but selective target mRNA destabilization in the macrophage transcriptome [RNA-Seq_2]
Precise control of mRNA decay is fundamental for robust yet not exaggerated inflammatory responses to pathogens. Parameters determining the specificity and extent of mRNA degradation within the entire inflammation-associated transcriptome remain incompletely understood. Using transcriptome-wide high...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-78209 | biostudies-arrayexpress
ProteomicsProtein Interactions of 7 MLL-fusion Proteins
MLL-fusions represent a large group of leukemia drivers, whose diversity originates from the vast molecular heterogeneity of C-terminal fusion partners of MLL protein. While studies of selected MLL-fusions have revealed critical molecular pathways, unifying mechanisms across all MLL-fusions remain p...
ORGANISM(S): Homo sapiens (Human) 
2018-05-25 | PXD009338 | Pride
Mll-fusion Leukemia Human 
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