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The eccrine sweat gland is an exocrine gland that is involved in the secretion of sweat for control of temperature. Malfunction of the sweat glands can result in disorders such as miliaria, hyperhidrosis and bromhidrosis. In addition, inadequate reabsorption of salt from sweat is a major feature of ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-15 | PXD010637 | Pride
The eccrine sweat gland is an exocrine gland that is involved in the secretion of sweat for control of temperature. Malfunction of the sweat glands can result in disorders such as miliaria, hyperhidrosis and bromhidrosis. In addition, inadequate reabsorption of salt from sweat is a major feature of ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-12 | MSV000084086 | MassIVE
K and Cl channels play critical role for sweat secretion, however, individual K or Cl channels and their functions are largely unknown. By comparing expreession profilings between wild-type and Eda mutant Tabby footpads we identified 4 K and 2 Cl channels highly expressed in mouse eccrine sweat glan...
ORGANISM(S): Mus musculus 
The potential of eccrine sweat as a bio-fluid of interest for diagnosis and personalized therapy has not yet been fully evaluated, due to the lack of in-depth sweat characterization studies. Thanks to recent developments in the field of omics together with the availability of accredited eccrine swea...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025899 | Pride
Integrated transcriptomic and proteomic analysis of human eccrine sweat glands
Sweat gland development requires an eccrine dermal niche and couples two epidermal programs
Eccrine porocarcinoma (EP) is the most common form of sweat gland malignancy. The aetiology of EP is largely unknown. The current lack of data on somatic mutation patterns in EP hampers the development of effective therapies. We performed whole-exome sequencing in a well-characterized sample of 14 m...
In clinical routine, the diagnosis of cystic fibrosis (CF) is still a challenge due to the limitations of diagnosis guidelines and tests. A diagnosis test of choice, the sweat test measures eccrine sweat chloride concentration as a byproduct of the eccrine sweat gland CFTR function. Despite the comb...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD028518 | Pride
Eccrine sweat glands are indispensable for human thermoregulation and, similar to other mammalian skin appendages, form from multipotent epidermal progenitors. Limited understanding of how epidermal progenitors specialize to form these vital organs has precluded therapeutic efforts toward their rege...
ORGANISM(S): Mus musculus 
2023-11-10 | GSE220977 | GEO
RNA seq-based transcriptome analysis of eccrine sweat glands from anhidrotic patients
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